Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.31 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.30 |
| ▸ | PIM1 | P11309 | 1/20 | 0.30 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21025761 | 0.81 | HCAR3 (0.38) | HTTKDM4EALDH1A1MAPTGAA | |
| SCHEMBL30980938 | 0.74 | HCAR3 (0.51) | KDM4EMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL28546794 | 0.74 | HCAR3 (0.51) | KDM4EMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL24913721 | 0.74 | HCAR3 (0.51) | KDM4EMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL13879940 | 0.70 | SIGMAR1 (0.37) | HTTKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL21026044 | 0.69 | HCAR3 (0.35) | HTTKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL18808003 | 0.69 | P2RX7 (0.35) | KMT2A | |
| SCHEMBL22158000 | 0.67 | AKR1C3 (0.42) | HTTMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL26507520 | 0.66 | KDM1A (0.38) | HTTMAPTPDE3BPDE3APIM1 | |
| SCHEMBL2185973 | 0.63 | ALOX15 (0.50) | HTTKDM4EMEN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230027088-A1 | EP300/CBP INHIBITOR | HINOVA PHARMACEUTICALS INC. (CN) | 2023-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230027088-A1 | EP300/CBP INHIBITOR | EP300, MLLT1, CREBBP | HTT 1822/4885KDM4E 143/4885MEN1 1021/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.