Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | GSK3A | P49840 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24916421 | 0.74 | MTNR1A (0.31) | — | |
| SCHEMBL13024156 | 0.66 | FFAR2 (0.58) | ALDH1A1LMNAKDM4ENPC1RAB9A | |
| SCHEMBL13827682 | 0.64 | ALDH1A1 (0.41) | ALDH1A1LMNAHSD17B10SMN1; SMN2KDM4E | |
| SCHEMBL11542523 | 0.64 | ALDH1A1 (0.44) | ALDH1A1HSD17B10MAPTSMN1; SMN2GAA | |
| SCHEMBL21853513 | 0.63 | SORT1 (0.38) | SORT1NOTUM | |
| SCHEMBL21853512 | 0.63 | SORT1 (0.38) | SORT1NOTUM | |
| SCHEMBL24754781 | 0.62 | ALDH1A1 (0.46) | ALDH1A1LMNAMAPTSMN1; SMN2KDM4E | |
| SCHEMBL12777978 | 0.62 | CCNE1 (0.40) | ALDH1A1MAPTSMN1; SMN2GAANPC1 | |
| SCHEMBL19755675 | 0.62 | KDM4E (0.43) | ALDH1A1MAPTSMN1; SMN2KDM4ENPC1 | |
| SCHEMBL3423922 | 0.62 | ALDH1A1 (0.42) | ALDH1A1LMNAHSD17B10MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230026466-A1 | WDR5 INHIBITORS AND MODULATORS | VANDERBILT UNIVERSITY | 2023-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230026466-A1 | WDR5 INHIBITORS AND MODULATORS | WDR5, WDR1, WDR3 | ALDH1A1 3815/4885LMNA 3551/4885HSD17B10 3158/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.