SCHEMBL24933946

SCHEMBL24933946

IN1c2ccccc2C2(c3ccccc3Oc3ccccc32)c2ccccc21

nearest known ligand 0.35

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
P2RX4 Q99571 11/20 0.35
ALOX5 P09917 1/20 0.34
CHRM3 P20309 1/20 0.33
AHR P35869 1/20 0.31
MAOA P21397 1/20 0.30
MAOB P27338 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3289558 0.81 ALOX5 (0.48) ALOX5CHRM3AHRMAOAMAOB
SCHEMBL19660995 0.81 MAPT (0.41) P2RX4ALOX5CHRM3MAOA
SCHEMBL15030643 0.78 ALDH1A1 (0.37) P2RX4ALOX5CHRM3
SCHEMBL21184892 0.78 MEN1 (0.41)
SCHEMBL13150242 0.77 P2RX4 (0.48) P2RX4ALOX5MAOAMAOB
SCHEMBL20229395 0.77 P2RX4 (0.39) P2RX4ALOX5CHRM3AHR
SCHEMBL19654648 0.77 CHRM3 (0.34) P2RX4ALOX5CHRM3
SCHEMBL20160481 0.74 LMNA (0.38) P2RX4
SCHEMBL21187241 0.73 MAOA (0.41) CHRM3MAOA
SCHEMBL5998195 0.73 KDM4E (0.43) ALOX5CHRM3AHRMAOAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023284022-A1 PHENANTHROIMIDAZOLE DERIVATIVE, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF 广东工业大学 2023-01-19 WO disclosed