SCHEMBL19660995

SCHEMBL19660995

CN1c2ccccc2C2(c3ccccc3Oc3ccccc32)c2ccccc21

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.41
KDM4E B2RXH2 2/20 0.41
LMNA P02545 2/20 0.41
HCRTR1 O43613 1/20 0.41
HTT P42858 2/20 0.39
USP2 O75604 2/20 0.39
MEN1 O00255 1/20 0.39
NPC1 O15118 1/20 0.39
POLB P06746 1/20 0.39
RAB9A P51151 1/20 0.39
KMT2A Q03164 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
ALDH1A1 P00352 1/20 0.38
CHRM3 P20309 1/20 0.36
MAOA P21397 1/20 0.36
P2RX4 Q99571 7/20 0.36
ALOX15 P16050 1/20 0.36
ALOX5 P09917 1/20 0.34
AKR1B1 P15121 1/20 0.34
RAD52 P43351 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3289558 0.81 ALOX5 (0.48) KDM4ECHRM3MAOAALOX5
SCHEMBL24933946 0.81 P2RX4 (0.35) CHRM3MAOAP2RX4ALOX5
SCHEMBL19654648 0.80 CHRM3 (0.34) CHRM3P2RX4ALOX5
SCHEMBL20229395 0.80 P2RX4 (0.39) MAPTUSP2SMN1; SMN2ALDH1A1CHRM3
SCHEMBL15030643 0.78 ALDH1A1 (0.37) ALDH1A1CHRM3P2RX4ALOX5
SCHEMBL11990876 0.78 MAPT (0.41) MAPTKDM4ELMNAHCRTR1HTT
SCHEMBL23056710 0.78 HTT (0.49) MAPTKDM4ELMNAHCRTR1HTT
SCHEMBL31067286 0.77 KDM4E (0.55) MAPTKDM4ERAB9ASMN1; SMN2ALDH1A1
SCHEMBL47007 0.77 KDM4E (0.55) MAPTKDM4ERAB9ASMN1; SMN2ALDH1A1
SCHEMBL24140666 0.75 ALOX5 (0.39) MAPTHTTUSP2MEN1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240239754-A1 PHENANTHROIMIDAZOLE DERIVATIVE, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF GUANGDONG UNIVERSITY OF TECHNOLOGY (CN) 2024-07-18 US disclosed
US-20240239754-A1 PHENANTHROIMIDAZOLE DERIVATIVE, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF GUANGDONG UNIVERSITY OF TECHNOLOGY (CN) 2024-07-18 US disclosed
US-20230137446-A1 THERMALLY ACTIVATED DELAYED FLUORESCENT MATERIAL, PREPARING METHOD THEREOF, AND ORGANIC ELECTROLUMINESCENT DEVICE WUHAN CHINA STAR OPTOELECTRONICS SEMICONDUCTOR DISPLAY TECHNOLOGY CO., LTD. (CN) 2023-05-04 US disclosed
US-20230137446-A1 THERMALLY ACTIVATED DELAYED FLUORESCENT MATERIAL, PREPARING METHOD THEREOF, AND ORGANIC ELECTROLUMINESCENT DEVICE WUHAN CHINA STAR OPTOELECTRONICS SEMICONDUCTOR DISPLAY TECHNOLOGY CO., LTD. (CN) 2023-05-04 US disclosed
US-11535605-B2 Electroluminesecent material, method for manufacturing the same and a luminesecent device with the electroluminesecent material WUHAN CHINA STAR OPTOELECTRONICS SEMICONDUCTOR DISPLAY TECHNOLOGY CO., LTD. (CN) 2022-12-27 US disclosed
US-11174427-B2 Aromatic compound and organic electroluminescence device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2021-11-16 US disclosed
US-20210351364-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT, DISPLAY DEVICE, AND LIGHTING DEVICE SK MATERIALS JNC CO., LTD. (KR) 2021-11-11 US disclosed
WO-2021036140-A1 ELECTROLUMINESCENT MATERIAL, PREPARATION METHOD OF ELECTROLUMINESCENT MATERIAL AND LIGHT-EMITTING DEVICE 武汉华星光电半导体显示技术有限公司 2021-03-04 WO disclosed
WO-2019143112-A1 ORGANIC ELECTROLUMINESCENT DEVICE 주식회사 두산 2019-07-25 WO disclosed
US-20180155617-A1 AROMATIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2018-06-07 US disclosed
US-20170346017-A1 NITROGEN-CONTAINING COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2017-11-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240239754-A1 PHENANTHROIMIDAZOLE DERIVATIVE, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF PAH, HTR3D, CYP3A4 MAPT 2223/4885KDM4E 621/4885LMNA 1921/4885
US-11535605-B2 Electroluminesecent material, method for manufacturing the same and a luminesecent device with the electroluminesecent material CYBA, ALG3, ACR MAPT 2200/4885KDM4E 2660/4885LMNA 1831/4885
US-20230137446-A1 THERMALLY ACTIVATED DELAYED FLUORESCENT MATERIAL, PREPARING METHOD THEREOF, AND ORGANIC ELECTROLUMINESCENT DEVICE DNTT, CD69, DUT MAPT 909/4885KDM4E 4140/4885LMNA 820/4885
US-20170346017-A1 NITROGEN-CONTAINING COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME NOM1, NOS1, NPM1 MAPT 1151/4885KDM4E 1836/4885LMNA 2657/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.