SCHEMBL24944714

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL26413827	0.90	SCN1A (0.51)	SCN1ASCN2ASCN3AOPRM1CHRNB2
	SCHEMBL24944624	0.86	OPRM1 (0.39)	OPRM1TSHR
	SCHEMBL24944854	0.84	HPGD (0.44)	OPRM1
	SCHEMBL24944222	0.82	SIGMAR1 (0.42)	OPRM1TSHR
	SCHEMBL26413848	0.82	SCN1A (0.46)	SCN1ASCN2ASCN3AOPRM1CHRNB2
	SCHEMBL24944295	0.82	NPC1 (0.49)	OPRM1
	SCHEMBL24944296	0.82	KEAP1 (0.45)	OPRM1
	SCHEMBL24943767	0.82	ALDH1A1 (0.49)	OPRM1RECQL
	SCHEMBL24944311	0.82	HPGD (0.44)	OPRM1TSHR
	SCHEMBL26413459	0.81	OPRM1 (0.39)	OPRM1RECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.