Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
| ▸ | IDO1 | P14902 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 2/20 | 0.56 |
| ▸ | CA12 | O43570 | 1/20 | 0.56 |
| ▸ | CA7 | P43166 | 1/20 | 0.56 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.56 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.53 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.50 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.48 |
| ▸ | CTSK | P43235 | 1/20 | 0.48 |
| ▸ | BCHE | P06276 | 1/20 | 0.48 |
| ▸ | SYK | P43405 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22605044 | 1.00 | ATM (0.58) | ATMIDO1CA1CA12CA7 | |
| SCHEMBL13426175 | 0.91 | ATM (0.55) | ATMIDO1CA1CA12CA7 | |
| SCHEMBL6559442 | 0.91 | ATM (0.55) | ATMIDO1CA1CA12CA7 | |
| SCHEMBL16151782 | 0.90 | MAOA (0.56) | ATMIDO1CA1CA12CA7 | |
| SCHEMBL22452275 | 0.89 | PPARG (0.52) | ATMIDO1CA1CA12CA7 | |
| SCHEMBL4709745 | 0.87 | PDCD1 (0.52) | ATMIDO1CA1PDCD1CD274 | |
| SCHEMBL21066539 | 0.87 | PDCD1 (0.49) | ATMIDO1CA1CA12CA7 | |
| SCHEMBL8399561 | 0.87 | IDO1 (0.55) | ATMIDO1CA1CA12CA7 | |
| SCHEMBL22783855 | 0.86 | KDM4E (0.53) | ATMIDO1CA1CA12CA7 | |
| SCHEMBL4704671 | 0.86 | IDO1 (0.50) | ATMIDO1CA1CA12CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 146 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4714499-A2 | POLYAMIDE COMPOUNDS, METHOD FOR PREPARING SAME, AND MEDICAL USE THEREOF | Jiangsu NHWA Pharmaceutical Co., Ltd (CN) | 2026-03-25 | — | — | EP | disclosed |
| US-20250230129-A1 | POLYAMIDE COMPOUNDS, METHOD FOR PREPARING SAME, AND MEDICAL USE THEREOF | JIANGSU NHWA PHARMACEUTICAL CO., LTD (CN) | 2025-07-17 | — | — | US | disclosed |
| EP-4497754-A1 | POLYAMIDE COMPOUNDS, METHOD FOR PREPARING SAME, AND MEDICAL USE THEREOF | Jiangsu NHWA Pharmaceutical Co., Ltd (CN) | 2025-01-29 | — | — | EP | disclosed |
| US-12157731-B2 | EIF4E inhibitors and uses thereof | PIC Therapeutics, Inc. (US) | 2024-12-03 | — | — | US | disclosed |
| US-20240309003-A1 | HETEROCYCLIC COMPOUNDS AS TRIGGERING RECEPTOR EXPRESSED ON MYELOID CELLS 2 AGONISTS AND METHODS OF USE | VIGIL NEUROSCIENCE, INC. (US) | 2024-09-19 | — | — | US | disclosed |
| US-20240293424-A1 | CARNITINE-PALMITOYL-TRANSFERASE-1 (CPT-1) INHIBITORS FOR USE IN A METHOD OF PREVENTING OR TREATING SEPSIS IN A MAMMALIAN SUBJECT | 2N PHARMA APS (DK) | 2024-09-05 | — | — | US | disclosed |
| US-20240246957-A1 | Diazepane Derivatives, Processes for their Preparation, and Uses thereof for the Amelioration, Prevention and/or Treatment of Mental and Neurological Diseases | 2N PHARMA APS (DK) | 2024-07-25 | — | — | US | disclosed |
| EP-4370129-A1 | CARNITINE-PALMITOYL-TRANSFERASE-1 (CPT-1) INHIBITORS FOR USE IN A METHOD OF PREVENTING OR TREATING SEPSIS IN A MAMMALIAN SUBJECT | 2N Pharma ApS (DK) | 2024-05-22 | — | — | EP | disclosed |
| EP-4334313-A1 | DIAZEPANE DERIVATIVES, PROCESSES FOR THEIR PREPARATION, AND USES THEREOF FOR THE AMELIORATION, PREVENTION AND/OR TREATMENT OF MENTAL AND NEUROLOGICAL DISEASES | 2N Pharma ApS (DK) | 2024-03-13 | — | — | EP | disclosed |
| EP-4334295-A2 | HETEROCYCLIC COMPOUNDS AS TRIGGERING RECEPTOR EXPRESSED ON MYELOID CELLS 2 AGONISTS AND METHODS OF USE | Vigil Neuoscience, Inc. (US) | 2024-03-13 | — | — | EP | disclosed |
| US-20080167491-A1 | T-butoxycarbonylaminoethylamine for the Synthesis of PNA Monomer Units, Amino Acid Derivatives, Intermediates Thereof, and Processes for Productions of Them | CREDIA JAPAN CO., LTD. (JP) | 2008-07-10 | — | — | US | disclosed |
| US-20080167491-A1 | T-butoxycarbonylaminoethylamine for the Synthesis of PNA Monomer Units, Amino Acid Derivatives, Intermediates Thereof, and Processes for Productions of Them | CREDIA JAPAN CO., LTD. (JP) | 2008-07-10 | — | — | US | disclosed |
| US-7351852-B2 | Simple and efficient preparation of an amino acid, alpha-tertiary-butoxycarbonylaminoethylamino-),alpha-(alkyl-)acetic acid; used to prepare peptide nucleic acids (PNA) including those having photosensitive functional groups; reduction step of benzyloxycarbonyl- omega -amino acid derivatives | CREDIA JAPAN CO., LTD. (JP) | 2008-04-01 | — | — | US | disclosed |
| US-7351852-B2 | Simple and efficient preparation of an amino acid, alpha-tertiary-butoxycarbonylaminoethylamino-),alpha-(alkyl-)acetic acid; used to prepare peptide nucleic acids (PNA) including those having photosensitive functional groups; reduction step of benzyloxycarbonyl- omega -amino acid derivatives | CREDIA JAPAN CO., LTD. (JP) | 2008-04-01 | — | — | US | disclosed |
| US-20070167457-A1 | N-AROYL PIPERAZINE DERIVATIVES AS OREXIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM PLC | 2007-07-19 | — | — | US | disclosed |
| WO-2007017092-A1 | SUBSTITUTED 4-BENZYLOXY-BENZOIC ACID AMIDE DERIVATIVES | BAYER HEALTHCARE AG (DE) | 2007-02-15 | — | — | WO | disclosed |
| US-7166608-B2 | N-aroyl piperazine derivatives as orexin receptor antagonists | SMITHKLINE BEECHAM P.L.C. (GB) | 2007-01-23 | — | — | US | disclosed |
| US-20040242575-A1 | N-aroyl piperazine derivatives as orexin receptor antagonists | SMITHKLINE BEECHAM P.L.C. (GB) | 2004-12-02 | — | — | US | disclosed |
| EP-1434583-A1 | N-AROYL PIPERAZINE DERIVATIVES AS OREXIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 2004-07-07 | — | — | EP | disclosed |
| WO-2003032991-A1 | N-AROYL PIPERAZINE DERIVATIVES AS OREXIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 2003-04-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240293424-A1 | CARNITINE-PALMITOYL-TRANSFERASE-1 (CPT-1) INHIBITORS FOR USE IN A METHOD OF PREVENTING OR TREATING SEPSIS IN A MAMMALIAN SUBJECT | CPT1A, CPT1B, CPT2 | ATM 2677/4885IDO1 1152/4885CA1 2879/4885 |
| US-20250230129-A1 | POLYAMIDE COMPOUNDS, METHOD FOR PREPARING SAME, AND MEDICAL USE THEREOF | ADCYAP1R1, PAICS, AGPS | ATM 4263/4885IDO1 1513/4885CA1 1076/4885 |
| US-20040242575-A1 | N-aroyl piperazine derivatives as orexin receptor antagonists | HCRTR2, HCRTR1, CNR1 | ATM 4720/4885IDO1 300/4885CA1 1454/4885 |
| US-20070167457-A1 | N-AROYL PIPERAZINE DERIVATIVES AS OREXIN RECEPTOR ANTAGONISTS | HCRTR2, HCRTR1, NPSR1 | ATM 4701/4885IDO1 527/4885CA1 1382/4885 |
| US-20080167491-A1 | T-butoxycarbonylaminoethylamine for the Synthesis of PNA Monomer Units, Amino Acid Derivatives, Intermediates Thereof, and Processes for Productions of Them | BCAT1, BCAT2, RNGTT | ATM 1697/4885IDO1 1650/4885CA1 1059/4885 |
| US-12157731-B2 | EIF4E inhibitors and uses thereof | EIF4E, EIF4EBP1, EIF4A1 | ATM 2461/4885IDO1 4758/4885CA1 4317/4885 |
| US-20240309003-A1 | HETEROCYCLIC COMPOUNDS AS TRIGGERING RECEPTOR EXPRESSED ON MYELOID CELLS 2 AGONISTS AND METHODS OF USE | MSR1, FPR2, CD14 | ATM 1627/4885IDO1 881/4885CA1 3334/4885 |
| US-20240246957-A1 | Diazepane Derivatives, Processes for their Preparation, and Uses thereof for the Amelioration, Prevention and/or Treatment of Mental and Neurological Diseases | SLC6A1, H1-3, GRIK3 | ATM 4353/4885IDO1 580/4885CA1 192/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.