Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 6/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8576453 | 0.86 | ALDH1A1 (0.48) | ALDH1A1TSHRTDP1ALOX12CA2 | |
| SCHEMBL10382469 | 0.80 | ALDH1A1 (0.43) | ALDH1A1TSHRTDP1ALOX12CA2 | |
| SCHEMBL31348027 | 0.80 | ALDH1A1 (0.43) | ALDH1A1TSHRTDP1ALOX12CA2 | |
| SCHEMBL8857069 | 0.78 | ALDH1A1 (0.41) | ALDH1A1TSHRTDP1ALOX12CA2 | |
| SCHEMBL29801228 | 0.77 | ALDH1A1 (0.50) | ALDH1A1TSHRTDP1ALOX12CA2 | |
| SCHEMBL27805 | 0.77 | ALDH1A1 (0.50) | ALDH1A1TSHRTDP1ALOX12CA2 | |
| SCHEMBL241267 | 0.77 | NFE2L2 (0.50) | ALDH1A1TSHRTDP1MAOBTNFRSF1A | |
| SCHEMBL241265 | 0.77 | NFE2L2 (0.50) | ALDH1A1TSHRTDP1MAOBTNFRSF1A | |
| SCHEMBL596277 | 0.77 | ALDH1A1 (0.48) | ALDH1A1TSHRTDP1ALOX12CA2 | |
| SCHEMBL5435012 | 0.77 | ALDH1A1 (0.48) | ALDH1A1TSHRTDP1ALOX12CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11572370-B2 | CD16A binding agents and uses thereof | BIOHAVEN THERAPEUTICS LTD. (US) | 2023-02-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11572370-B2 | CD16A binding agents and uses thereof | FCGR1A, FCGR2A, FCGR3B | ALDH1A1 1203/4885TSHR 1233/4885TDP1 2251/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.