Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 2/20 | 0.81 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | CYP11B2 | P19099 | 5/20 | 0.49 |
| ▸ | CYP17A1 | P05093 | 3/20 | 0.49 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.49 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.45 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1623940 | 0.90 | KIF11 (1.00) | KIF11CYP19A1CYP3A4CYP2C19CYP2D6 | |
| SCHEMBL23666164 | 0.90 | KIF11 (1.00) | KIF11CYP19A1CYP3A4CYP2C19CYP2D6 | |
| SCHEMBL10150461 | 0.85 | LMNA (0.56) | KIF11CYP19A1ALDH1A1THRBCYP11B2 | |
| SCHEMBL2250286 | 0.82 | KIF11 (0.83) | KIF11CYP19A1CYP3A4ALDH1A1THRB | |
| SCHEMBL21345924 | 0.81 | CYP3A4 (0.57) | KIF11CYP19A1CYP3A4CYP2C19CYP2D6 | |
| SCHEMBL21346444 | 0.81 | ALDH1A1 (0.52) | KIF11ALDH1A1THRBNPC1HPGD | |
| SCHEMBL22904695 | 0.81 | KIF11 (0.77) | KIF11CYP3A4CYP2D6ALDH1A1NPC1 | |
| SCHEMBL7013344 | 0.81 | CYP11B2 (0.60) | KIF11CYP19A1CYP3A4CYP2C19CYP2D6 | |
| SCHEMBL23394825 | 0.80 | RAB9A (0.68) | KIF11ALDH1A1NPC1HPGDRAB9A | |
| SCHEMBL18934226 | 0.80 | RAB9A (0.68) | KIF11ALDH1A1NPC1HPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11572337-B2 | Antibacterial agents: arylalkylcarboxamido phloroglucinols | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2023-02-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11572337-B2 | Antibacterial agents: arylalkylcarboxamido phloroglucinols | RNGTT, FBL, POLR1C | KIF11 773/4885CYP19A1 3021/4885CYP3A4 1953/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.