Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.37 |
| ▸ | CDK9 | P50750 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25004046 | 0.84 | L3MBTL1 (0.40) | SMN1; SMN2L3MBTL1TDP1TSHRHSD17B10 | |
| SCHEMBL25003226 | 0.74 | HTR3A (0.36) | L3MBTL1TDP1TSHRHSD17B10ALDH1A1 | |
| SCHEMBL18286388 | 0.72 | BRD4 (0.43) | SMN1; SMN2L3MBTL1TDP1TSHRHSD17B10 | |
| SCHEMBL1757958 | 0.70 | L3MBTL1 (0.42) | SMN1; SMN2L3MBTL1TDP1TSHRHSD17B10 | |
| SCHEMBL21904789 | 0.70 | L3MBTL1 (0.42) | SMN1; SMN2L3MBTL1TDP1TSHRHSD17B10 | |
| SCHEMBL25003917 | 0.70 | ALDH1A1 (0.52) | SMN1; SMN2L3MBTL1TDP1TSHRHSD17B10 | |
| SCHEMBL22094637 | 0.69 | SMN1; SMN2 (0.38) | SMN1; SMN2L3MBTL1TDP1TSHRHSD17B10 | |
| SCHEMBL31309060 | 0.69 | SMN1; SMN2 (0.38) | SMN1; SMN2L3MBTL1TDP1TSHRHSD17B10 | |
| SCHEMBL9914279 | 0.67 | TSHR (0.38) | SMN1; SMN2TDP1TSHRALDH1A1CYP2C9 | |
| SCHEMBL20689952 | 0.66 | GPR84 (0.50) | ALDH1A1CCNT1CDK9LMNACDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230045421-A1 | SUBSTITUTED ARYLMETHYLUREAS AND HETEROARYLMETHYLUREAS, ANALOGUES THEREOF, AND METHODS USING SAME | ARBUTUS BIOPHARMA CORP (CA) | 2023-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230045421-A1 | SUBSTITUTED ARYLMETHYLUREAS AND HETEROARYLMETHYLUREAS, ANALOGUES THEREOF, AND METHODS USING SAME | HAVCR2, HMBS, AHCY | SMN1; SMN2 3865/4885L3MBTL1 959/4885TDP1 3687/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.