SCHEMBL250541

SCHEMBL250541

C[Si](C)(C)OC1(c2ccccc2)CCC[Si](c2ccccc2)(c2ccccc2)O1

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2360760 0.82 OPRM1 (0.30)
SCHEMBL28854635 0.77
SCHEMBL27567572 0.76 AKR1C1 (0.33) EPHX2
SCHEMBL2352430 0.73 AKR1C1 (0.35)
SCHEMBL182249 0.72
SCHEMBL7107826 0.71
Ammonia Solution, Strong SCHEMBL7586755 0.70
SCHEMBL17721898 0.70
SCHEMBL27994036 0.68 SMN1; SMN2 (0.31)
SCHEMBL18094240 0.68 SMN1; SMN2 (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1635 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115315246-A Solid composition in the form of a water-in-oil emulsion 莱雅公司 2022-11-08 CN claimed
EP-3883653-A1 COSMETIC MAKE-UP COMPOSITION WITH LONG-LASTING SKIN-PERFECTING EFFECT L V M H RECHERCHE (FR) 2021-09-29 EP claimed
CN-112351821-A Composition comprising a saturated fatty alcohol, at least one fatty chain anionic surfactant, a polyol and at least one silicone oil 莱雅公司 2021-02-09 CN claimed
CN-112137902-A Moisturizing, concealer and anti-wrinkle composition and preparation method thereof 青岛姿之妍化妆品科技有限责任公司 2020-12-29 CN claimed
US-10729641-B2 Ordered macroporous materials REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 2020-08-04 US claimed
CN-111449990-A Non-volatile silicone oil cosmetic composition and preparation method thereof 嘉兴市华盛化妆品有限公司 2020-07-28 CN claimed
EP-3236930-B1 DISPERSION OF POLYMER PARTICLES IN A NON-AQUEOUS MEDIUM AND COSMETIC USE THEREOF OREAL (FR) 2020-02-05 EP claimed
US-20180214370-A1 TOPCOAT FOR LONG-WEAR LIP COMPOSITIONS L'OREAL (FR) 2018-08-02 US claimed
EP-3086761-B1 AQUEOUS COSMETIC COMPOSITION COMPRISING ALKYLCELLULOSE, NON-VOLATILE OILS, A HYDROPHILIC GELLING POLYMER AND A POLYOL OREAL (FR) 2018-05-16 EP claimed
EP-3236930-A1 DISPERSION OF POLYMER PARTICLES IN A NON-AQUEOUS MEDIUM AND COSMETIC USE THEREOF L'Oréal (FR) 2017-11-01 EP claimed
US-20020064509-A1 Method for producing a goniochromatic effect comprising applying to skin a cosmetic composition comprising at least one continuous lipophilic phase and at least one goniochromatic pigment L'OREAL S.A. (FR) 2002-05-30 US claimed
US-20020058054-A1 Transfer-resistant cosmetic compositions comprising a non-volatile silicone compound, a non-volatile hydrocarbon-based oil, and an inert particular phase L'OREAL (FR) 2002-05-16 US claimed
WO-2002017861-A1 MATT COSMETIC COMPOSITION COMPRISING A NON-VOLATILE HYDROCARBON OIL AND AN INERT PARTICULATE PHASE L'OREAL (FR) 2002-03-07 WO claimed
EP-1184028-A1 Non-transfer cosmetic composition comprising a non-volatile silicone, a non-volatile hydrocarbon oil and an inert particulate phase L'OREAL (FR) 2002-03-06 EP claimed
CN-1331966-A Care or make-up composition containing fiber and hydrophilic polysiloxane OREAL (FR) 2002-01-23 CN claimed
US-20010031269-A1 Transfer-resistant cosmetic composition comprising a non-volatile silicone compound and a non-volatile hydrocarbon-based oil which is incompatible with this silicone compound L'OREAL (FR) 2001-10-18 US claimed
CN-1302596-A Alkyl non volatile oil cosmetic composition for preventing shading OREAL (FR) 2001-07-11 CN claimed
EP-1112734-A2 Non-transfer cosmetic composition comprising a non-volatile silicon compound, and a non-volatile hydrocarbon oil incompatible with the silicone compound L'OREAL (FR) 2001-07-04 EP claimed
CN-1256119-A Cosmetic composition containg at least one kind of amorphous poly(cyclenes) or amorphous poly(cyclenes) mixture and its use OREAL (FR) 2000-06-14 CN claimed
CN-1240639-A Composition of olefin copolymer comprising controlled crystallization and use of such coplymer OREAL (FR) 2000-01-12 CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010031269-A1 Transfer-resistant cosmetic composition comprising a non-volatile silicone compound and a non-volatile hydrocarbon-based oil which is incompatible with this silicone compound CUTA, PRDM9, GIGYF2 EPHX2 2033/4885
US-20180214370-A1 TOPCOAT FOR LONG-WEAR LIP COMPOSITIONS LIPC, LIPA, LPL EPHX2 1176/4885
US-20020058054-A1 Transfer-resistant cosmetic compositions comprising a non-volatile silicone compound, a non-volatile hydrocarbon-based oil, and an inert particular phase CUTA, GRN, NONO EPHX2 1114/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.