SCHEMBL25065758

SCHEMBL25065758

COc1c(-c2ccc(O)c(O)c2)oc2cccc(OC)c2c1=O

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.70
POLB P06746 2/20 0.70
MAPT P10636 2/20 0.70
KMT2A Q03164 2/20 0.70
KDM4E B2RXH2 1/20 0.70
MMP1 P03956 1/20 0.70
GAA P10253 1/20 0.70
APEX1 P27695 1/20 0.70
HTT P42858 1/20 0.70
RECQL P46063 1/20 0.70
BLM P54132 1/20 0.70
HSD17B10 Q99714 1/20 0.70
POLH Q9Y253 1/20 0.70
XDH P47989 1/20 0.70
NOX4 Q9NPH5 2/20 0.68
PLG P00747 1/20 0.68
TUBB4A P04350 2/20 0.63
TUBB P07437 2/20 0.63
TUBA3C P0DPH7 2/20 0.63
TUBA1B P68363 2/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7660030 0.90 NOX4 (0.76) MEN1POLBMAPTKMT2AKDM4E
SCHEMBL31304741 0.88 POLB (0.82) MEN1POLBMAPTKMT2AKDM4E
SCHEMBL11149169 0.88 POLB (0.82) MEN1POLBMAPTKMT2AKDM4E
SCHEMBL30284949 0.88 POLB (0.82) MEN1POLBMAPTKMT2AKDM4E
SCHEMBL15635393 0.86 PLG (0.82) MEN1POLBMAPTKMT2AKDM4E
SCHEMBL2928366 0.85 XDH (0.78) MEN1POLBMAPTKMT2AKDM4E
Chrysosplenol D SCHEMBL29359614 0.85 ALOX5 (0.83) MEN1POLBMAPTKMT2AKDM4E
Chrysosplenol D SCHEMBL11133546 0.85 ALOX5 (0.83) MEN1POLBMAPTKMT2AKDM4E
SCHEMBL8656946 0.84 ALOX5 (0.75) MEN1POLBMAPTKMT2AKDM4E
SCHEMBL29024597 0.83 ALOX5 (0.76) MEN1POLBMAPTKMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230056314-A1 CYTOPROTECTIVE COMPOSITIONS FOR SHORT-TERM CELLS STORAGE AND TRANSPORTATION WITHOUT CRYOPRESERVATION AND DEEP FREEZING Reelabs Private Limited, a Company Incorporated Under Provisions of The Companies Act 1956 (IN) 2023-02-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230056314-A1 CYTOPROTECTIVE COMPOSITIONS FOR SHORT-TERM CELLS STORAGE AND TRANSPORTATION WITHOUT CRYOPRESERVATION AND DEEP FREEZING BCL2, SLC14A1, TXN2 MEN1 3761/4885POLB 1856/4885MAPT 427/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.