Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 4/20 | 0.39 |
| ▸ | BACE2 | Q9Y5Z0 | 2/20 | 0.39 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.39 |
| ▸ | CDK9 | P50750 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.35 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.34 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.34 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12160709 | 0.78 | ALDH1A1 (0.44) | CNR2EGLN2NAMPTSMN1; SMN2KDM4E | |
| SCHEMBL19287728 | 0.74 | BACE1 (0.46) | BACE1BACE2CDK9CNR2MAPK1 | |
| SCHEMBL12176285 | 0.73 | MAPT (0.42) | CNR2EGLN2NAMPTKDM4EALDH1A1 | |
| SCHEMBL21163853 | 0.73 | MAPT (0.42) | CNR2EGLN2NAMPTKDM4EALDH1A1 | |
| SCHEMBL19121669 | 0.71 | ADRA2C (0.39) | SMN1; SMN2KDM4EALDH1A1MAPTP2RX3 | |
| SCHEMBL17852320 | 0.71 | TRPC5 (0.48) | BACE1CNR2EGLN2NAMPTSMN1; SMN2 | |
| SCHEMBL22699596 | 0.70 | EPHX1 (0.45) | CCNT1CDK9CNR2DRD4NAMPT | |
| SCHEMBL19121498 | 0.70 | LMNA (0.40) | BACE1BACE2SMN1; SMN2KDM4E | |
| SCHEMBL24302650 | 0.68 | RORC (0.43) | BACE1BACE2P2RX3 | |
| SCHEMBL13836012 | 0.68 | BACE1 (0.52) | BACE1BACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023020209-A1 | UREA COMPOUND CONTAINING 2-HETEROAROMATIC RING SUBSTITUTION, PREPARATION METHOD THEREFOR AND USE THEREOF | 中国科学院上海药物研究所 | 2023-02-23 | — | — | WO | disclosed |