SCHEMBL251035

SCHEMBL251035

c1ccc2c(-c3nnc(-c4cccc5ccccc45)s3)cccc2c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.53
ALDH1A1 P00352 2/20 0.53
LMNA P02545 1/20 0.53
HPGD P15428 1/20 0.53
HSD17B10 Q99714 1/20 0.53
PTPN11 Q06124 1/20 0.52
HDAC1 Q13547 1/20 0.50
HDAC2 Q92769 1/20 0.50
ALOX15 P16050 2/20 0.47
DCTPP1 Q9H773 1/20 0.47
HTR2C P28335 2/20 0.46
TGFBR1 P36897 1/20 0.44
CYP11B2 P19099 1/20 0.42
NPC1 O15118 2/20 0.42
MAPT P10636 2/20 0.42
RAB9A P51151 2/20 0.42
ATM Q13315 1/20 0.42
MGAM O43451 1/20 0.42
GAA P10253 1/20 0.42
SI P14410 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12914313 0.96 PTPN11 (0.50) KDM4EALDH1A1LMNAHPGDHSD17B10
SCHEMBL30987378 0.91 PTPN11 (0.47) KDM4EALDH1A1LMNAHPGDHSD17B10
SCHEMBL27646939 0.89 GUSB (0.49) KDM4EALDH1A1LMNAHPGDHSD17B10
SCHEMBL27639574 0.88 GUSB (0.48) KDM4EALDH1A1LMNAHPGDHSD17B10
SCHEMBL27620753 0.88 GUSB (0.51) KDM4EALDH1A1LMNAHPGDHSD17B10
SCHEMBL1107963 0.87 KDM4E (0.47) KDM4EALDH1A1LMNAHPGDHSD17B10
SCHEMBL28827251 0.87 KDM4E (0.61) KDM4EALDH1A1LMNAHPGDHSD17B10
SCHEMBL1531740 0.87 PTPN11 (0.47) KDM4EALDH1A1LMNAHPGDHSD17B10
SCHEMBL17819129 0.84 ALOX15 (0.54) KDM4EALDH1A1LMNAHPGDHSD17B10
SCHEMBL9341530 0.83 PTPN11 (0.45) KDM4EALDH1A1LMNAHPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 295 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240334821-A1 Electroluminescent Device UDC IRELAND LTD (IE) 2024-10-03 US disclosed
US-11968893-B2 Electroluminescent device UDC IRELAND LIMITED (IE) 2024-04-23 US disclosed
US-20220216422-A1 Electroluminescent Device UDC IRELAND LTD (IE) 2022-07-07 US disclosed
US-11345686-B2 Aromatic amine derivative, and organic electroluminescent element IDEMITSU KOSAN CO., LTD. (JP) 2022-05-31 US disclosed
US-11289658-B2 Electroluminescent device UDC IRELAND LIMITED (IE) 2022-03-29 US disclosed
EP-2315502-B1 Electroluminescent device UDC IRELAND LTD (IE) 2020-10-14 EP disclosed
US-10454038-B2 Delayed-fluorescence material and organic electroluminescence element using same KYULUX, INC. (JP) 2019-10-22 US disclosed
US-20190237675-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE UTILIZING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2019-08-01 US disclosed
US-20190177306-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2019-06-13 US disclosed
US-10312452-B2 Aromatic amine derivative and organic electroluminescence device utilizing the same IDEMITSU KOSAN CO., LTD. (JP) 2019-06-04 US disclosed
EP-1061112-A1 ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN COMPANY LIMITED (JP) 2000-12-20 EP disclosed
US-6150042-A ELECTROLUMINESCENCE DEVICE WITH HOLE INJECTING MATERIAL HAVING GOOD DURABILITY BEING A TRIPHENYLENE STRUCTURE OF GIVEN FORMULA HAVING MULTIPLE ETHER, SULFIDE, AND/OR AMINE SUBSTITUTIONS TOYO INK MANUFACTURING CO., LTD. (JP) 2000-11-21 US disclosed
EP-0965629-A1 Compound for organic electroluminescence device and organic electroluminescence device TOYO INK MFG. CO., LTD. (JP) 1999-12-22 EP disclosed
EP-0934992-A1 Light-emitting material for organo-electroluminescence device and organic electroluminescence device TOYO INK MANUFACTURING CO., LTD. (JP) 1999-08-11 EP disclosed
EP-0866110-A1 Light-emitting material for organo-electroluminescence device and organic electroluminescence device TOYO INK MANUFACTURING CO., LTD. (JP) 1998-09-23 EP disclosed
US-5811834-A Light-emitting material for organo-electroluminescence device and organo-electroluminescence device for which the light-emitting material is adapted TOYO INK MANUFACTURING CO., LTD. (JP) 1998-09-22 US disclosed
EP-0847228-A2 Material for organoelectroluminescence device and use thereof TOYO INK MANUFACTURING CO., LTD. (JP) 1998-06-10 EP disclosed
US-5759444-A FLAT LIGHT SOURCE OR DISPLAY; BRIGHTNESS, STABILITY TOYO INK MANUFACTURING CO., LTD. (JP) 1998-06-02 US disclosed
EP-0786926-A2 Light-emitting material for organo-electroluminescence device and organo-electroluminescence devive for which the light-emitting material is adapted TOYO INK MANUFACTURING CO., LTD. (JP) 1997-07-30 EP disclosed
EP-0765106-A2 Light-emitting material for organic electroluminescence device, and organic electroluminescence device for which the light-emitting material is adapted TOYO INK MANUFACTURING CO., LTD. (JP) 1997-03-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240334821-A1 Electroluminescent Device PNPO, ODC1, AXL KDM4E 1312/4885ALDH1A1 436/4885LMNA 4324/4885
US-10312452-B2 Aromatic amine derivative and organic electroluminescence device utilizing the same TYR, OCIAD2, MAOA KDM4E 375/4885ALDH1A1 397/4885LMNA 2273/4885
US-20190177306-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT TYR, LEF1, EFNA1 KDM4E 191/4885ALDH1A1 263/4885LMNA 1720/4885
US-11289658-B2 Electroluminescent device PNPO, ODC1, AXL KDM4E 1312/4885ALDH1A1 436/4885LMNA 4324/4885
US-20220216422-A1 Electroluminescent Device PNPO, ODC1, AXL KDM4E 1312/4885ALDH1A1 436/4885LMNA 4324/4885
US-10454038-B2 Delayed-fluorescence material and organic electroluminescence element using same HNRNPF, RABL6, SRSF6 KDM4E 2926/4885ALDH1A1 2141/4885LMNA 2132/4885
US-11345686-B2 Aromatic amine derivative, and organic electroluminescent element TYR, LEF1, EFNA1 KDM4E 191/4885ALDH1A1 263/4885LMNA 1720/4885
US-11968893-B2 Electroluminescent device PNPO, ODC1, AXL KDM4E 1312/4885ALDH1A1 436/4885LMNA 4324/4885
US-20190237675-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE UTILIZING THE SAME TYR, NLRP1, NLRP3 KDM4E 511/4885ALDH1A1 498/4885LMNA 2737/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.