Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 2/20 | 0.35 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.33 |
| ▸ | KDM5C | P41229 | 2/20 | 0.33 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.33 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.33 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.33 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.33 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.33 |
| ▸ | TACR3 | P29371 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.33 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.33 |
| ▸ | BRS3 | P32247 | 1/20 | 0.33 |
| ▸ | JMJD6 | Q6NYC1 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL175672 | 0.89 | CCR1 (0.38) | KDM5AKDM5BPSEN1PSEN2APH1B | |
| Bromide SCHEMBL2514869 | 0.86 | CCR1 (0.35) | KDM5AKDM5BPOLBALDH1A1 | |
| SCHEMBL145233 | 0.83 | CCR1 (0.33) | BRS3POLBALDH1A1 | |
| SCHEMBL3040111 | 0.83 | NR1I2 (0.39) | KDM5AKDM5BKDM4CPSEN1PSEN2 | |
| SCHEMBL174988 | 0.83 | NR1I2 (0.39) | KDM5AKDM4E | |
| SCHEMBL4308271 | 0.79 | — | — | |
| SCHEMBL13039644 | 0.78 | LNPEP (0.37) | KDM4E | |
| SCHEMBL5974098 | 0.77 | NR1I2 (0.47) | KDM5AKDM4E | |
| SCHEMBL6417924 | 0.77 | KDM5A (0.50) | KDM5AKDM5BKDM4CKDM5CKDM4E | |
| SCHEMBL2136994 | 0.75 | ALDH1A1 (0.35) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8034971-B2 | Method for producing 1,2-phenylethane compound using atom transfer radical coupling reaction | NIPPON SODA CO., LTD. (JP) | 2011-10-11 | — | — | US | disclosed |
| US-20090275772-A1 | Metrod for Producing 1,2-Phenylethane Compound Using Atom Transfer Radical Coupling Reaction | NIPPON SODA CO., LTD. (JP) | 2009-11-05 | — | — | US | disclosed |
| EP-1997798-A1 | METHOD FOR PRODUCING 1,2-PHENYLETHANE COMPOUND USING ATOM TRANSFER RADICAL COUPLING REACTION | Nippon Soda Co., Ltd. (JP) | 2008-12-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090275772-A1 | Metrod for Producing 1,2-Phenylethane Compound Using Atom Transfer Radical Coupling Reaction | ROS1, MET, MT-CO1 | KDM5A 2732/4885KDM5B 2937/4885KDM4C 3273/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.