SCHEMBL2513752

SCHEMBL2513752

O=C(OF)C(F)(F)[I+](c1ccccc1)c1ccccc1

nearest known ligand 0.36

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CES1 P23141 3/20 0.36
KCNN4 O15554 1/20 0.33
CTRB1 P17538 1/20 0.33
PTPN1 P18031 1/20 0.31
CES2 O00748 1/20 0.31
ACHE P22303 1/20 0.31
SRC P12931 1/20 0.31
BACE1 P56817 1/20 0.30
POLB P06746 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30
F2 P00734 1/20 0.30
LMNA P02545 1/20 0.30
HDAC1 Q13547 1/20 0.30
HDAC2 Q92769 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2514635 0.87 CES2 (0.42) CES1CES2ACHE
SCHEMBL2510736 0.79 TRPV1 (0.37) LMNAHDAC1
SCHEMBL2451645 0.69 KCNN4 (0.45) CES1KCNN4PTPN1CES2LMNA
SCHEMBL29095960 0.68 KCNN4 (0.44) CES1KCNN4PTPN1CES2LMNA
Hydrochloric Acid SCHEMBL29145555 0.68 KCNN4 (0.44) CES1KCNN4PTPN1CES2LMNA
SCHEMBL27568720 0.68 KCNN4 (0.44) CES1KCNN4PTPN1BACE1POLB
SCHEMBL8583194 0.67 KCNN4 (0.42) CES1KCNN4CTRB1PTPN1CES2
SCHEMBL107377 0.67 CES1 (0.42) CES1KCNN4PTPN1CES2ACHE
SCHEMBL27545668 0.67 CES1 (0.38) CES1KCNN4HDAC1HDAC2
SCHEMBL1406732 0.67 ALDH1A1 (0.41) CES1PTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130289316-A1 OPTICALLY ISOTROPIC LIQUID CRYSTAL MEDIUM AND OPTICAL DEVICE JNC CORP (JP) 2013-10-31 US disclosed
US-8455061-B2 Optically active compound having polymerizable group and its polymer JNC CORPORATION (JP) 2013-06-04 US disclosed
US-20130100369-A1 COMPOUND HAVING BRANCHED ALKYL OR BRANCHED ALKENYL, OPTICALLY ISOTROPIC LIQUID CRYSTAL MEDIUM AND OPTICAL ELEMENT JNC PETROCHEMICAL CORPORATION (JP) 2013-04-25 US disclosed
US-20110240918-A1 OPTICALLY ACTIVE COMPOUND HAVING POLYMERIZABLE GROUP AND ITS POLYMER CHISSO CORPORATION (JP) 2011-10-06 US disclosed