Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 2/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 3/20 | 0.37 |
| ▸ | MAPK9 | P45984 | 3/20 | 0.37 |
| ▸ | CSNK1D | P48730 | 3/20 | 0.37 |
| ▸ | MINK1 | Q8N4C8 | 3/20 | 0.37 |
| ▸ | PRKD2 | Q9BZL6 | 3/20 | 0.37 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | FAP | Q12884 | 1/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.34 |
| ▸ | GCGR | P47871 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23023590 | 0.84 | PTGS2 (0.44) | PTGS2HTR6ADORA2AADORA2BADORA1 | |
| SCHEMBL23023565 | 0.78 | PTGS2 (0.42) | PTGS2HTR6ADORA2AADORA2BMAPK9 | |
| SCHEMBL23023679 | 0.74 | SLC34A1 (0.43) | PTGS2HTR6GRM5SLC34A1 | |
| SCHEMBL21526649 | 0.69 | ALDH1A1 (0.41) | PTGS2HTR6ADORA2AADORA1 | |
| SCHEMBL25150620 | 0.69 | MAOB (0.41) | — | |
| SCHEMBL23023602 | 0.68 | HTR6 (0.41) | PTGS2HTR6ADORA2AADORA2BADORA1 | |
| SCHEMBL9752941 | 0.67 | ALDH1A1 (0.35) | PTGS2ADORA2AADORA2BADORA1MAP4K4 | |
| SCHEMBL9753098 | 0.67 | GCGR (0.40) | ADORA2AADORA2BADORA1MAP4K4MAPK9 | |
| SCHEMBL23023571 | 0.66 | ADORA2A (0.40) | PTGS2HTR6ADORA2AADORA2BADORA1 | |
| SCHEMBL23023705 | 0.66 | MAP4K4 (0.41) | ADORA2AADORA2BADORA1MAP4K4MAPK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11634425-B2 | Pharmaceutical compounds | PFIZER INC. (US) | 2023-04-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11634425-B2 | Pharmaceutical compounds | GABRA6, CHRNA6, CNR1 | PTGS2 3812/4885HTR6 169/4885ADORA2A 989/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.