Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL250159 | 0.75 | HTT (0.38) | HTTSMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL249197 | 0.74 | ALDH1A1 (0.32) | ALDH1A1MEN1KMT2AKDM4ECYP1A2 | |
| SCHEMBL6516855 | 0.72 | CREBBP (0.39) | ALDH1A1MEN1KMT2AKDM4ECYP1A2 | |
| SCHEMBL249020 | 0.71 | HTT (0.37) | HTTSMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL31562726 | 0.66 | KDM4E (0.35) | ALDH1A1MEN1KMT2AKDM4ECYP1A2 | |
| SCHEMBL3056776 | 0.66 | CREBBP (0.35) | ALDH1A1MEN1KMT2AKDM4ECYP1A2 | |
| SCHEMBL22721439 | 0.66 | ALDH1A1 (0.52) | ALDH1A1MEN1KMT2AKDM4ECYP1A2 | |
| SCHEMBL31562390 | 0.66 | CREBBP (0.35) | ALDH1A1MEN1KMT2AKDM4ECYP1A2 | |
| SCHEMBL2012936 | 0.63 | ALDH1A1 (0.46) | SMN1; SMN2ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL28246281 | 0.62 | ALDH1A1 (0.35) | HTTALDH1A1MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012001308-A9 | METHOD FOR SYNTHESIZING ERGOLINE ALKALOIDS FROM INDOLIC BICYCLIC COMPOUNDS BY DOUBLE CYCLIZATION, RESULTING MATERIALS, AND INTERMEDIATE MATERIALS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2012-03-22 | — | — | WO | disclosed |
| WO-2012001308-A1 | METHOD FOR SYNTHESIZING ERGOLINE ALKALOIDS FROM INDOLIC BICYCLIC COMPOUNDS BY DOUBLE CYCLIZATION, RESULTING MATERIALS, AND INTERMEDIATE MATERIALS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2012-01-05 | — | — | WO | disclosed |