Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 2/20 | 0.39 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.39 |
| ▸ | CTSK | P43235 | 4/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
| ▸ | CTSB | P07858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5175528 | 0.89 | ALOX15 (0.36) | CTSKEGLN1ALOX15HSD17B10 | |
| SCHEMBL10695446 | 0.89 | GPR84 (0.38) | PRKCAPRKCDCTSKCTSLCTSB | |
| SCHEMBL8460905 | 0.88 | MAPT (0.34) | PRKCAPRKCDCTSKALOX15HSD17B10 | |
| SCHEMBL11430759 | 0.87 | CTSK (0.44) | PRKCAPRKCDCTSKALOX15HSD17B10 | |
| SCHEMBL11689448 | 0.86 | PRKCA (0.39) | PRKCAPRKCDCTSKCA1CA2 | |
| SCHEMBL8462672 | 0.84 | ALOX15 (0.33) | EGLN1ALOX15HSD17B10 | |
| Itaconate SCHEMBL28623652 | 0.83 | ALOX15 (0.42) | PRKCAPRKCDCTSKALOX15HSD17B10 | |
| SCHEMBL27990138 | 0.83 | CTSK (0.40) | PRKCAPRKCDCTSKALOX15HSD17B10 | |
| SCHEMBL28292545 | 0.81 | CACNA2D1 (0.33) | CTSKALOX15HSD17B10ADRA1A | |
| SCHEMBL10396700 | 0.81 | CHRM1 (0.33) | ALOX15HSD17B10CHRM1AKR1A1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102307854-B | Mixtures of itaconic acid or itaconic acid derivatives with primary amines for the preparation of 1, 3-and 1, 4-alkylmethylpyrrolidones | BASF SE | 2014-11-12 | — | — | CN | disclosed |
| US-8796472-B2 | Mixtures of itaconic acid or itaconic acid derivatives and primary amines for producing 1,3- and 1,4-alkyl methyl pyrrolidones | BASF SE (DE) | 2014-08-05 | — | — | US | disclosed |
| CN-102307854-A | Mixtures of itaconic acid or itaconic acid derivatives with primary amines for the preparation of 1, 3-and 1, 4-alkylmethylpyrrolidones | BASF SE | 2012-01-04 | — | — | CN | disclosed |
| US-20110251119-A1 | MIXTURES OF ITACONIC ACID OR ITACONIC ACID DERIVATIVES AND PRIMARY AMINES FOR PRODUCING 1,3- AND 1,4-ALKYL METHYL PYRROLIDONES | BASF SE (DE) | 2011-10-13 | — | — | US | disclosed |
| US-4051194-A | Thermosetting resin composition for powder paint comprising of a (I) polymer consisting of β-methylglycidyl (meth)acrylate, styrene, unsaturated dialkyl ester, alkylacrylate and (II) saturated aliphatic dibasic acid | DAINIPPON INK AND CHEMICALS, INC. (JA) | 1977-09-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110251119-A1 | MIXTURES OF ITACONIC ACID OR ITACONIC ACID DERIVATIVES AND PRIMARY AMINES FOR PRODUCING 1,3- AND 1,4-ALKYL METHYL PYRROLIDONES | HADHA, HADH, ASS1 | PRKCA 3344/4885PRKCD 3043/4885CTSK 3966/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.