Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 4/20 | 0.44 |
| ▸ | PTGES | O14684 | 1/20 | 0.43 |
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2519287 | 1.00 | ALOX5 (0.44) | ALOX5PTGESNOX1MAOBLMNA | |
| SCHEMBL2523598 | 0.85 | PRKCA (0.39) | ALOX5PTGESNOX1MAOBLMNA | |
| SCHEMBL2523594 | 0.85 | PRKCA (0.39) | ALOX5PTGESNOX1MAOBLMNA | |
| SCHEMBL2522672 | 0.84 | NR1H4 (0.47) | LMNAL3MBTL1 | |
| SCHEMBL27220461 | 0.74 | NOX1 (0.54) | ALOX5NOX1MAOBLMNALTA4H | |
| SCHEMBL1424355 | 0.71 | OPRM1 (0.35) | — | |
| SCHEMBL3642587 | 0.71 | DGAT1 (0.39) | — | |
| SCHEMBL12208122 | 0.70 | MRGPRX4 (0.39) | LMNA | |
| SCHEMBL5702266 | 0.69 | L3MBTL1 (0.63) | ALOX5PTGESNOX1MAOBLMNA | |
| SCHEMBL9375612 | 0.67 | NOX1 (0.59) | ALOX5NOX1MAOBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110251173-A1 | CHEMICAL COMPOUNDS | ASTRAZENECA AB (SE) | 2011-10-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110251173-A1 | CHEMICAL COMPOUNDS | DGAT1, DGAT2, SLC5A1 | ALOX5 3266/4885PTGES 1358/4885NOX1 2602/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.