Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3988149 | 0.89 | TSHR (0.60) | THRBTSHRALDH1A1TDP1POLB | |
| SCHEMBL6358410 | 0.88 | TSHR (0.63) | THRBTSHRALDH1A1TDP1POLB | |
| SCHEMBL8608732 | 0.86 | TSHR (0.67) | THRBTSHRALDH1A1TDP1POLB | |
| SCHEMBL23031388 | 0.84 | THRB (0.52) | THRBTSHRALDH1A1TDP1POLB | |
| Urea SCHEMBL15263286 | 0.84 | THRB (0.65) | THRBTSHRALDH1A1TDP1POLB | |
| SCHEMBL3818412 | 0.83 | THRB (0.50) | THRBTSHRALDH1A1TDP1POLB | |
| SCHEMBL2453478 | 0.82 | THRB (0.57) | THRBTSHRALDH1A1TDP1POLB | |
| SCHEMBL9312977 | 0.82 | THRB (0.57) | THRBTSHRALDH1A1TDP1POLB | |
| SCHEMBL587661 | 0.82 | THRB (0.57) | THRBTSHRALDH1A1TDP1POLB | |
| SCHEMBL10426403 | 0.82 | THRB (0.57) | THRBTSHRALDH1A1TDP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150164853-A1 | PROSTACYCLIN COMPOSITIONS FOR REGULATION OF FRACTURE REPAIR AND BONE FORMATION | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH | 2015-06-18 | — | — | US | claimed |
| US-20110251677-A1 | Coating Designs For The Tailored Release Of Dual Drugs From Polymeric Coatings | ABBOTT CARDIOVASCULAR SYSTEMS INC. (US) | 2011-10-13 | — | — | US | claimed |
| WO-2009055306-A2 | COATING DESIGNS FOR THE TAILORED RELEASE OF DUAL DRUGS FROM POLYMERIC COATINGS | ABBOTT CARDIOVASCULAR SYSTEMS INC. (US) | 2009-04-30 | — | — | WO | claimed |
| US-20090104247-A1 | Coating Designs For The Tailored Release Of Dual Drugs From Polymeric Coatings | ABBOTT CARDIOVASCULAR SYSTEMS INC. | 2009-04-23 | — | — | US | claimed |
| JP-6247917-A | — | — | None | — | — | JP | disclosed |
| EP-3782599-B1 | DENTAL POLYMERIZABLE COMPOSITION BASED ON CONDENSED SILANES | VOCO GMBH (DE) | 2025-09-17 | — | — | EP | disclosed |
| US-11992538-B2 | Polymerizable dental composition based on condensed silanes | VOCO GMBH (DE) | 2024-05-28 | — | — | US | disclosed |
| CN-109666163-B | Hybrid crosslinked dynamic polymer and application thereof | 厦门逍扬运动科技有限公司 | 2023-05-12 | — | — | CN | disclosed |
| US-20210052469-A1 | POLYMERIZABLE DENTAL COMPOSITION BASED ON CONDENSED SILANES | VOCO GMBH (DE) | 2021-02-25 | — | — | US | disclosed |
| US-20210052469-A1 | POLYMERIZABLE DENTAL COMPOSITION BASED ON CONDENSED SILANES | VOCO GMBH (DE) | 2021-02-25 | — | — | US | disclosed |
| EP-3782599-A1 | DENTAL POLYMERIZABLE COMPOSITION BASED ON CONDENSED SILANES | VOCO GmbH (DE) | 2021-02-24 | — | — | EP | disclosed |
| EP-3782599-A1 | DENTAL POLYMERIZABLE COMPOSITION BASED ON CONDENSED SILANES | VOCO GmbH (DE) | 2021-02-24 | — | — | EP | disclosed |
| US-20080124450-A1 | copolymerizing an amino acid mimetic monomer and hydrophobic acrylate monomers; amino acid mimetic monomers selected to mimic the side chain of the amino acids Asn or gln can be a (meth)acryloyl derivative of 2-hydroxyacetamide, 3-hydroxypropionamide, alaninamide, lactamide; biocompatible; coated stent | ABBOTT LABORATORIES (US) | 2008-05-29 | — | — | US | disclosed |
| US-20080125514-A1 | Biocompatible polymers that include an amino acid mimetic monomer and one or more hydrophobic acrylate monomers, the amino acid mimetic monomers being selected to mimic the side chain of the amino acids asparagine or glutamine; mechanical strength, drug permeability | ABBOTT LABORATORIES (US) | 2008-05-29 | — | — | US | disclosed |
| US-20080125514-A1 | Biocompatible polymers that include an amino acid mimetic monomer and one or more hydrophobic acrylate monomers, the amino acid mimetic monomers being selected to mimic the side chain of the amino acids asparagine or glutamine; mechanical strength, drug permeability | ABBOTT LABORATORIES (US) | 2008-05-29 | — | — | US | disclosed |
| US-20080124450-A1 | copolymerizing an amino acid mimetic monomer and hydrophobic acrylate monomers; amino acid mimetic monomers selected to mimic the side chain of the amino acids Asn or gln can be a (meth)acryloyl derivative of 2-hydroxyacetamide, 3-hydroxypropionamide, alaninamide, lactamide; biocompatible; coated stent | ABBOTT LABORATORIES (US) | 2008-05-29 | — | — | US | disclosed |
| WO-2006041559-A1 | ADHESION PROMOTING COMPOSITION AND METHOD | BASF CORPORATION (US) | 2006-04-20 | — | — | WO | disclosed |
| US-20060074163-A1 | An adhesion promoting formulation includes a polymer, such as an acrylic copolymer, having acetoacetoxy functionality and adhesion-promoting functionality and a metal alkoxide, chelate, and/or alkoxide chelate; coating over a metal surface or coated surface; refinishing; automobiles | BASF CORPORATION (US) | 2006-04-06 | — | — | US | disclosed |
| JP-H06247917-A | PRODUCTION OF N-SUBSTITUTED CARBAMOYLETHYL (METH) ACRYLATE | NIPPON SHOKUBAI CO LTD | 1994-09-06 | — | — | JP | disclosed |
| EP-0172427-A2 | Process for production of vinyl chloride polymer | Shin-Etsu Chemical Co., Ltd. (JP) | 1986-02-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150164853-A1 | PROSTACYCLIN COMPOSITIONS FOR REGULATION OF FRACTURE REPAIR AND BONE FORMATION | PTGIR, PTGIS, PTGS1 | THRB 1853/4885TSHR 3190/4885ALDH1A1 3437/4885 |
| US-11992538-B2 | Polymerizable dental composition based on condensed silanes | NCAPH, RCC1, NCAPD2 | THRB 4522/4885TSHR 4596/4885ALDH1A1 1481/4885 |
| US-20210052469-A1 | POLYMERIZABLE DENTAL COMPOSITION BASED ON CONDENSED SILANES | NCAPH, RCC1, NCAPD2 | THRB 4522/4885TSHR 4596/4885ALDH1A1 1481/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.