SCHEMBL2522239

SCHEMBL2522239

[CH2]c1c2ccccc2c([CH2])c2ccccc12

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.41
HSD17B10 Q99714 4/20 0.41
CYP2A6 P11509 3/20 0.41
TDP1 Q9NUW8 2/20 0.41
TSHR P16473 1/20 0.41
CYP1A2 P05177 4/20 0.39
IDO1 P14902 1/20 0.39
GPR3 P46089 4/20 0.37
HPRT1 P00492 1/20 0.37
KDM4E B2RXH2 2/20 0.35
MAPK1 P28482 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
ALOX12 P18054 1/20 0.33
ATM Q13315 1/20 0.33
HIF1A Q16665 1/20 0.33
CYP1B1 Q16678 1/20 0.33
THRB P10828 1/20 0.33
HPGD P15428 1/20 0.33
MEN1 O00255 1/20 0.32
CYP3A4 P08684 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15352181 0.84 CYP2A6 (0.32) ALDH1A1HSD17B10CYP2A6TDP1TSHR
SCHEMBL5872355 0.78 L3MBTL1 (0.54) CYP2A6CYP1A2MEN1KMT2A
SCHEMBL40471 0.77 ALDH1A1 (0.50) ALDH1A1HSD17B10CYP2A6TDP1TSHR
SCHEMBL2883734 0.75 ALDH1A1 (0.56) ALDH1A1HSD17B10TDP1TSHRCYP1A2
SCHEMBL3250828 0.73
SCHEMBL3246428 0.73 CYP1A2 (0.39) ALDH1A1HSD17B10CYP2A6TDP1TSHR
SCHEMBL5251509 0.73 KDM4E (0.37) ALDH1A1HSD17B10TDP1TSHRIDO1
SCHEMBL11806091 0.72 ALDH1A1 (0.39) ALDH1A1HSD17B10CYP2A6TDP1TSHR
Triphenylene SCHEMBL25597 0.71 HPRT1 (0.57) ALDH1A1HSD17B10CYP2A6TDP1TSHR
SCHEMBL1006251 0.71 HPRT1 (0.57) ALDH1A1HSD17B10CYP2A6TDP1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240192202-A1 FLUIDIC MEDIA FOR SINGLE-ANALTYE ARRAYS NAUTILUS SUBSIDIARY INC (US) 2024-06-13 US claimed
WO-2024124073-A1 A METHOD COMPRISING PERFORMING ON A SINGLE-ANALYTE ARRAY AT LEAST 50 CYCLES OF A PROCESS NAUTILUS SUBSIDIARY, INC. (US) 2024-06-13 WO claimed
EP-2141545-A1 Phosphonate containing photoconductors Xerox Corporation (US) 2010-01-06 EP claimed
EP-2128709-A1 Phosphonate Hole Blocking Layer Photoconductors Xerox Corporation (US) 2009-12-02 EP claimed
WO-2024130000-A1 INHIBITION OF PHOTON PHENOMENA ON SINGLE MOLECULE ARRAYS NAUTILUS SUBSIDIARY, INC. (US) 2024-06-20 WO disclosed
US-20240201182-A1 INHIBITION OF PHOTON PHENOMENA ON SINGLE MOLECULE ARRAYS NAUTILUS SUBSIDIARY, INC. 2024-06-20 US disclosed
WO-2024124073-A1 A METHOD COMPRISING PERFORMING ON A SINGLE-ANALYTE ARRAY AT LEAST 50 CYCLES OF A PROCESS NAUTILUS SUBSIDIARY, INC. (US) 2024-06-13 WO disclosed
US-20240192202-A1 FLUIDIC MEDIA FOR SINGLE-ANALTYE ARRAYS NAUTILUS SUBSIDIARY INC (US) 2024-06-13 US disclosed
US-11944682-B2 Aggregation induced emission-bacteriophage bioconjugates The Hong Kong University of Science and Technologyy (CN) 2024-04-02 US disclosed
US-11882831-B2 Substituted thiophene oligomers and polymers UNM RAINFOREST INNOVATIONS (US) 2024-01-30 US disclosed
US-20220132843-A1 SUBSTITUTED THIOPHENE OLIGOMERS AND POLYMERS UNM RAINFOREST INNOVATIONS 2022-05-05 US disclosed
US-11154059-B2 Substituted thiophene oligomers and polymers UNITED STATES DEPARTMENT OF ENERGY 2021-10-26 US disclosed
CN-101223826-A Method for luminescent layer formation and organic electroluminescent device DAINIPPON PRINTING CO LTD (JP) 2008-07-16 CN disclosed
WO-2006123813-A1 METHOD FOR LUMINESCENT LAYER FORMATION AND ORGANIC ELECTROLUMINESCENT DEVICE DAI NIPPON PRINTING CO., LTD. (JP) 2006-11-23 WO disclosed
EP-1599744-A2 SELF-INDICATING RADIATION ALERT DOSIMETER JP LABORATORIES, INC. (US) 2005-11-30 EP disclosed
WO-2004077097-A2 SELF-INDICATING RADIATION ALERT DOSIMETER JP LABORATORIES INC. (US) 2004-09-10 WO disclosed
EP-0903965-B1 MULTICOLOR ORGANIC EL ELEMENT, METHOD FOR MANUFACTURING THE SAME, AND DISPLAY USING THE SAME CHEMIPRO KASEI KAISHA LTD (JP) 2003-07-30 EP disclosed
US-6459199-B1 Multicolor organic EL element having plurality of organic dyes, method of manufacturing the same, and display using the same CHEMIPRO KASEI KAISHA, LIMITED (JP) 2002-10-01 US disclosed
EP-1162193-A1 Acrylenediamine derivatives and organic electroluminescence device containing the same IDEMITSU KOSAN COMPANY LIMITED (JP) 2001-12-12 EP disclosed
EP-0903965-A1 MULTICOLOR ORGANIC EL ELEMENT, METHOD FOR MANUFACTURING THE SAME, AND DISPLAY USING THE SAME CHEMIPRO KASEI KAISHA, LIMITED (JP) 1999-03-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11882831-B2 Substituted thiophene oligomers and polymers TST, NOD2, CLPP ALDH1A1 4119/4885HSD17B10 2025/4885CYP2A6 3838/4885
US-20220132843-A1 SUBSTITUTED THIOPHENE OLIGOMERS AND POLYMERS TST, NOD2, CLPP ALDH1A1 4119/4885HSD17B10 2025/4885CYP2A6 3838/4885
US-11944682-B2 Aggregation induced emission-bacteriophage bioconjugates MLN, POLL, FUS ALDH1A1 3889/4885HSD17B10 4734/4885CYP2A6 3765/4885
US-11154059-B2 Substituted thiophene oligomers and polymers TST, NOD2, CLPP ALDH1A1 4119/4885HSD17B10 2025/4885CYP2A6 3838/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.