SCHEMBL2433050

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2433373	0.88	TDP1 (0.38)	TDP1KDM1APDE4APDE4BPDE4C
	SCHEMBL2523334	0.85	PDE4A (0.41)	TDP1KDM1APDE4APDE4BPDE4C
	SCHEMBL1136059	0.82	MET (0.40)	TDP1KDM1APDE4APDE4BPDE4C
	SCHEMBL1136191	0.79	MET (0.38)	TDP1IDO1CHRM2CHRM1CHRM3
	SCHEMBL2437380	0.75	FFAR1 (0.39)	PDE4APDE4BPDE4CPDE4DPARP15
	SCHEMBL2433379	0.72	PDE4D (0.38)	PDE4APDE4BPDE4CPDE4DIDO1
	SCHEMBL1136023	0.71	GPR84 (0.41)	TDP1KDM4ENPC1ALDH1A1CYP3A4
	SCHEMBL2432159	0.71	NPC1 (0.37)	IDO1METKDM4ENPC1ALDH1A1
	SCHEMBL2430302	0.71	ALDH1A1 (0.46)	IDO1CNR1KDM4ENPC1ALDH1A1
	SCHEMBL2432859	0.71	ADORA3 (0.43)	TDP1IDO1METKDM4ENPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.