Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.34 |
| ▸ | MEN1 | O00255 | 5/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4501238 | 0.94 | ALDH1A1 (0.35) | NPSR1ALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL3732991 | 0.85 | ALDH1A1 (0.32) | NPSR1ALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL2947754 | 0.84 | KMT2A (0.33) | NPSR1ALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL728293 | 0.84 | ALDH1A1 (0.34) | NPSR1ALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL6290176 | 0.84 | MEN1 (0.35) | NPSR1ALDH1A1KMT2AMEN1POLB | |
| SCHEMBL2525179 | 0.77 | P2RX7 (0.32) | NPSR1KMT2AMEN1POLBMAPK1 | |
| SCHEMBL1153522 | 0.75 | MEN1 (0.39) | ALDH1A1KMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL7958362 | 0.75 | CXCR5 (0.39) | ALDH1A1TSHR | |
| SCHEMBL2071170 | 0.74 | CYP2C19 (0.40) | ALDH1A1KMT2AMEN1 | |
| SCHEMBL2433660 | 0.73 | TSHR (0.36) | KMT2AMEN1MAPTSMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8039014-B2 | 3′-alkoxyspirocyclopentyl-substituted tetramic and tetronic acids | BAYER CROPSCIENCE AG (DE) | 2011-10-18 | — | — | US | disclosed |
| US-20100004127-A1 | 3'-ALKOXYSPIROCYCLOPENTYL-SUBSTITUTED TETRAMIC AND TETRONIC ACIDS | BAYER CROPSCIENCE AG (DE) | 2010-01-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100004127-A1 | 3'-ALKOXYSPIROCYCLOPENTYL-SUBSTITUTED TETRAMIC AND TETRONIC ACIDS | TPI1, PPA1, PTPRG | NPSR1 2833/4885ALDH1A1 4189/4885KMT2A 3773/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.