Dimethylformamide

Dimethylformamide

SCHEMBL25263371

CN(C)C=O.Cc1c(C(=O)O)ccc2c1OC(C)O2

nearest known ligand 0.32

Full drug profile on Sugi Atlas →

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32
POLB P06746 1/20 0.32
HPGD P15428 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
MAPK1 P28482 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21496548 0.90 MAPK1 (0.36) ALDH1A1POLBHPGDSMN1; SMN2L3MBTL1
Trifluoroacetic Acid SCHEMBL23142462 0.82 PTGS2 (0.35) ALDH1A1HPGDMAPK1
SCHEMBL27829365 0.76 PARP1 (0.41) ALDH1A1
SCHEMBL6182009 0.73 MAPK1 (0.35) ALDH1A1POLBHPGDSMN1; SMN2L3MBTL1
SCHEMBL23142463 0.68
SCHEMBL13060339 0.66 ALDH1A1 (0.36) ALDH1A1POLBHPGDSMN1; SMN2L3MBTL1
SCHEMBL8595403 0.64 PRKAB2 (0.43) ALDH1A1POLBHPGDSMN1; SMN2MAPK1
SCHEMBL3761317 0.64 PRKAB2 (0.43) ALDH1A1POLBHPGDSMN1; SMN2MAPK1
SCHEMBL2427291 0.63 ALDH1A1 (0.44) ALDH1A1HPGDSMN1; SMN2MAPK1
SCHEMBL2427488 0.63 KDM4E (0.55) ALDH1A1HPGDSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023135564-A1 1,3-BENZODIOXOLE DERIVATIVE COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING SAME 동화약품주식회사 2023-07-20 WO disclosed