Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 11/20 | 0.59 |
| ▸ | HSD17B2 | P37059 | 11/20 | 0.59 |
| ▸ | PLAU | P00749 | 1/20 | 0.59 |
| ▸ | ESR1 | P03372 | 2/20 | 0.55 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.48 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.44 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.44 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.44 |
| ▸ | NQO2 | P16083 | 1/20 | 0.43 |
| ▸ | CA3 | P07451 | 1/20 | 0.43 |
| ▸ | CA6 | P23280 | 1/20 | 0.43 |
| ▸ | CA5A | P35218 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31556780 | 1.00 | HSD17B1 (0.59) | HSD17B1HSD17B2PLAUESR1ESR2 | |
| SCHEMBL28296698 | 0.83 | CYP1A2 (0.45) | HSD17B1HSD17B2PLAUESR1ESR2 | |
| SCHEMBL6552818 | 0.83 | CTDSP1 (0.59) | HSD17B1HSD17B2PLAUESR1ESR2 | |
| SCHEMBL29738652 | 0.77 | HSD17B1 (0.70) | HSD17B1HSD17B2PLAUESR1ESR2 | |
| SCHEMBL30366550 | 0.77 | CYP1A2 (0.52) | HSD17B1HSD17B2CYP1A2CYP2A6CA3 | |
| SCHEMBL29364213 | 0.77 | HSD17B1 (0.70) | HSD17B1HSD17B2PLAUESR1ESR2 | |
| SCHEMBL5748246 | 0.77 | CYP1A2 (0.52) | HSD17B1HSD17B2CYP1A2CYP2A6CA3 | |
| SCHEMBL444105 | 0.77 | HSD17B1 (0.84) | HSD17B1HSD17B2PLAUESR1ESR2 | |
| SCHEMBL18530961 | 0.77 | CYP1A2 (0.52) | HSD17B1HSD17B2ESR1ESR2CYP1A2 | |
| SCHEMBL15451 | 0.77 | HSD17B1 (0.70) | HSD17B1HSD17B2PLAUESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 93 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12599672-B2 | KRAS proteolysis targeting chimeras | PAQ Therapeutics Inc. (US) | 2026-04-14 | — | — | US | disclosed |
| US-20260078111-A1 | CARBONIC ANHYDRASE ENZYME INHIBITORS AND METHODS OF USE THEREOF | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2026-03-19 | — | — | US | disclosed |
| EP-4630401-A2 | CARBONIC ANHYDRASE ENZYME INHIBITORS AND METHODS OF USE THEREOF | Rutgers, the State University of New Jersey (US) | 2025-10-15 | — | — | EP | disclosed |
| US-20250144225-A1 | KRAS Proteolysis Targeting Chimeras | PAQ Therapeutics Inc. (US) | 2025-05-08 | — | — | US | disclosed |
| US-20250025443-A1 | COMPOUNDS AND METHODS FOR TREATING CORONA VIRUSES | Clear Creek Bio, Inc. (US) | 2025-01-23 | — | — | US | disclosed |
| US-12152041-B2 | Macrocyclic fluorine substituted indole derivatives | THE BROAD INSTITUTE, INC. (US) | 2024-11-26 | — | — | US | disclosed |
| WO-2024124023-A2 | CARBONIC ANHYDRASE ENZYME INHIBITORS AND METHODS OF USE THEREOF | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2024-06-13 | — | — | WO | disclosed |
| CN-111989321-B | KRAS G12C inhibitors | 米拉蒂治疗股份有限公司 | 2024-05-14 | — | — | CN | disclosed |
| US-20240101553-A1 | KRAS G12C INHIBITORS | MIRATI THERAPEUTICS INC (US) | 2024-03-28 | — | — | US | disclosed |
| US-11891404-B2 | Substituted macrocyclic indole derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 2024-02-06 | — | — | US | disclosed |
| WO-2007008389-A2 | USE OF COLOR CHANGING INDICATORS IN CONSUMER PRODUCTS | C2C TECHNOLOGIES LLC (US) | 2007-01-18 | — | — | WO | disclosed |
| US-20070010400-A1 | Use of color changing indicators in consumer products | C2C TECHNOLOGIES, LLC | 2007-01-11 | — | — | US | disclosed |
| US-20060257439-A1 | Cleansing compositions with color changing indicator | CRAYOLA LLC | 2006-11-16 | — | — | US | disclosed |
| US-20060236470-A1 | Novelty compositions with color changing indicator | CRAYOLA LLC | 2006-10-26 | — | — | US | disclosed |
| WO-2006105193-A2 | PERSONAL CARE COMPOSITIONS WITH COLOR CHANGING INDICATOR | C2C TECHNOLOGIES LLC (US) | 2006-10-05 | — | — | WO | disclosed |
| WO-2006105261-A1 | CLEANSING COMPOSITIONS WITH COLOR CHANGING INDICATOR | C2C TECHNOLOGIES LLC (US) | 2006-10-05 | — | — | WO | disclosed |
| WO-2006105260-A1 | ORAL CARE COMPOSITIONS WITH COLOR CHANGING INDICATOR | C2C TECHNOLOGIES LLC (US) | 2006-10-05 | — | — | WO | disclosed |
| WO-2006105191-A2 | NOVELTY COMPOSITIONS WITH COLOR CHANGING INDICATOR | C2C TECHNOLOGIES LLC (US) | 2006-10-05 | — | — | WO | disclosed |
| US-20060222601-A1 | Oral care compositions with color changing indicator | C2C TECHNOLOGIES, LLC | 2006-10-05 | — | — | US | disclosed |
| US-20060222675-A1 | Personal care compositions with color changing indicator | C2C TECHNOLOGIES, LLC | 2006-10-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060222675-A1 | Personal care compositions with color changing indicator | CUTA, POLR1C, TYR | HSD17B1 912/4885HSD17B2 807/4885PLAU 2600/4885 |
| US-12599672-B2 | KRAS proteolysis targeting chimeras | KRAS, HRAS, NRAS | HSD17B1 4005/4885HSD17B2 4145/4885PLAU 3358/4885 |
| US-12152041-B2 | Macrocyclic fluorine substituted indole derivatives | FOXM1, CCNT2, CCND2 | HSD17B1 2297/4885HSD17B2 2141/4885PLAU 4698/4885 |
| US-20060257439-A1 | Cleansing compositions with color changing indicator | WASHC5, WASHC4, FHIT | HSD17B1 3695/4885HSD17B2 3227/4885PLAU 2509/4885 |
| US-11891404-B2 | Substituted macrocyclic indole derivatives | FOXM1, CCND2, CCNI | HSD17B1 1807/4885HSD17B2 1673/4885PLAU 4688/4885 |
| US-20250144225-A1 | KRAS Proteolysis Targeting Chimeras | KRAS, HRAS, NRAS | HSD17B1 4065/4885HSD17B2 4251/4885PLAU 1603/4885 |
| US-20240101553-A1 | KRAS G12C INHIBITORS | KRAS, NRAS, HRAS | HSD17B1 3232/4885HSD17B2 3797/4885PLAU 3981/4885 |
| US-20060222601-A1 | Oral care compositions with color changing indicator | CA9, CA7, TAS2R7 | HSD17B1 2554/4885HSD17B2 2489/4885PLAU 3721/4885 |
| US-20070010400-A1 | Use of color changing indicators in consumer products | NQO2, CA4, CA7 | HSD17B1 1323/4885HSD17B2 981/4885PLAU 3680/4885 |
| US-20260078111-A1 | CARBONIC ANHYDRASE ENZYME INHIBITORS AND METHODS OF USE THEREOF | CA6, CA9, CA7 | HSD17B1 68/4885HSD17B2 167/4885PLAU 2040/4885 |
| US-20060236470-A1 | Novelty compositions with color changing indicator | MITF, CRABP2, SHH | HSD17B1 3009/4885HSD17B2 2797/4885PLAU 2331/4885 |
| US-20250025443-A1 | COMPOUNDS AND METHODS FOR TREATING CORONA VIRUSES | ACE, PREP, PEPD | HSD17B1 2428/4885HSD17B2 2965/4885PLAU 70/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.