SCHEMBL25311656

SCHEMBL25311656

COC(=O)c1ccc(Oc2cccc(Oc3ccc(C(=O)OC)cc3)c2C#N)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.50
CA2 P00918 2/20 0.50
USP2 O75604 1/20 0.48
MAPT P10636 3/20 0.46
TDP1 Q9NUW8 2/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
RAB9A P51151 3/20 0.45
ALDH1A1 P00352 3/20 0.44
KMT2A Q03164 3/20 0.44
TSHR P16473 1/20 0.44
POLB P06746 3/20 0.44
SMN1; SMN2 Q16637 3/20 0.44
NPC1 O15118 2/20 0.44
LMNA P02545 1/20 0.44
BLM P54132 1/20 0.44
CA12 O43570 1/20 0.43
CA7 P43166 1/20 0.43
CA9 Q16790 1/20 0.43
CA14 Q9ULX7 1/20 0.43
MAPK14 Q16539 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27860600 0.92 POLB (0.49) CA1CA2USP2MAPTTDP1
SCHEMBL8560809 0.84 POLB (0.65) CA1CA2MAPTTDP1L3MBTL1
SCHEMBL18914706 0.83 EZH2 (0.40) CA1CA2USP2MAPTTDP1
SCHEMBL28253414 0.83 LPAR1 (0.52) CA1CA2MAPTMAPK14LPAR1
SCHEMBL20091515 0.82 EZH2 (0.39) CA1CA2USP2MAPTTDP1
SCHEMBL11411879 0.82 CA1 (0.62) CA1CA2MAPTTDP1L3MBTL1
SCHEMBL9242685 0.79 RAB9A (0.65) CA1CA2MAPTTDP1L3MBTL1
SCHEMBL10723558 0.78 LMNA (0.46) MAPTTDP1ALDH1A1KMT2APOLB
SCHEMBL1339129 0.78 USP2 (0.57) CA1CA2USP2MAPTTDP1
SCHEMBL8466237 0.78 PARP10 (0.46) MAPTTDP1ALDH1A1KMT2ATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12559589-B2 High-temperature self-crosslinking-based flame-retardant anti-dripping copolyester, and preparation method therefor and application thereof SICHUAN UNIVERSITY (CN) 2026-02-24 US disclosed
US-20230235116-A1 HIGH-TEMPERATURE SELF-CROSSLINKING-BASED FLAME-RETARDANT ANTI-DRIPPING COPOLYESTER, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF SICHUAN UNIVERSITY (CN) 2023-07-27 US disclosed
EP-4169967-A1 HIGH-TEMPERATURE SELF-CROSSLINKING-BASED FLAME-RETARDANT DROPLET-RESISTANT COPOLYESTER, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF Sichuan University (CN) 2023-04-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12559589-B2 High-temperature self-crosslinking-based flame-retardant anti-dripping copolyester, and preparation method therefor and application thereof COL1A1, F11, COL2A1 CA1 1744/4885CA2 1930/4885USP2 2337/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.