SCHEMBL25314219

SCHEMBL25314219

CCc1cc(Cc2cc(CC)c(NC(=O)C(C)(C)C)c(CC)c2)cc(CC)c1NC(=O)C(C)(C)C

nearest known ligand 0.42

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
NPC1 O15118 1/20 0.37
RAB9A P51151 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
GAA P10253 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
MAPT P10636 4/20 0.36
ALDH1A1 P00352 4/20 0.36
KDM4E B2RXH2 2/20 0.36
HPGD P15428 2/20 0.36
SOAT1 P35610 1/20 0.36
USP2 O75604 1/20 0.36
HSPA5 P11021 1/20 0.35
LMNA P02545 1/20 0.35
CETP P11597 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25311825 0.81 HTT (0.57) HTTL3MBTL1NPC1RAB9ASMN1; SMN2
SCHEMBL12666586 0.78 CYP2C19 (0.50) HTTL3MBTL1NPSR1MAPTALDH1A1
SCHEMBL8103433 0.77 GAA (0.35) HTTGAANPSR1MAPTALDH1A1
SCHEMBL12284735 0.76 GAA (0.50) L3MBTL1SMN1; SMN2GAANPSR1MAPT
SCHEMBL13129145 0.72 PTPN1 (0.45) NPC1RAB9ASMN1; SMN2GAAMAPT
SCHEMBL13129142 0.72 HPGD (0.50) RAB9AALDH1A1KDM4EHPGDCETP
SCHEMBL9861529 0.72 SHBG (0.34) HTTSMN1; SMN2GAAHPGDHSPA5
SCHEMBL12284575 0.71 LMNA (0.50) HTTL3MBTL1SMN1; SMN2GAAALDH1A1
SCHEMBL12285477 0.71 KDM4E (0.54) HTTNPC1RAB9ASMN1; SMN2NPSR1
SCHEMBL24777788 0.70 L3MBTL1 (0.46) HTTL3MBTL1NPSR1MAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12630693-B2 Small-cell polystyrene foams, and process for producing same INEOS STYROLUTION GROUP GMBH (DE) 2026-05-19 US disclosed
EP-4153668-B1 SMALL-CELL POLYSTYRENE FOAMS, AND PROCESS FOR PRODUCING SAME INEOS STYROLUTION GROUP GMBH (DE) 2024-08-28 EP disclosed
US-20230227627-A1 SMALL-CELL POLYSTYRENE FOAMS, AND PROCESS FOR PRODUCING SAME INEOS STYROLUTION GROUP GMBH (DE) 2023-07-20 US disclosed
EP-4153668-A1 SMALL-CELL POLYSTYRENE FOAMS, AND PROCESS FOR PRODUCING SAME INEOS Styrolution Group GmbH (DE) 2023-03-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230227627-A1 SMALL-CELL POLYSTYRENE FOAMS, AND PROCESS FOR PRODUCING SAME F12, FDFT1, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 HTT 960/4885L3MBTL1 790/4885NPC1 1606/4885
US-12630693-B2 Small-cell polystyrene foams, and process for producing same H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, CBR1, CBR3 HTT 2433/4885L3MBTL1 864/4885NPC1 1529/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.