SCHEMBL25337696

SCHEMBL25337696

Cn1c(SCC(=O)N2CCCCC2)nnc1-c1ccccc1

nearest known ligand 0.79

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.79
SMN1; SMN2 Q16637 4/20 0.79
LMNA P02545 2/20 0.79
RGS12 O14924 1/20 0.79
NPSR1 Q6W5P4 1/20 0.79
HSD17B10 Q99714 2/20 0.70
MAPT P10636 2/20 0.70
KDM4E B2RXH2 3/20 0.69
TP53 P04637 2/20 0.66
NPC1 O15118 1/20 0.66
RAB9A P51151 1/20 0.66
TSHR P16473 1/20 0.66
HPGD P15428 2/20 0.65
KMT2A Q03164 2/20 0.65
MEN1 O00255 1/20 0.62
POLB P06746 1/20 0.61
RECQL P46063 1/20 0.61
MCL1 Q07820 1/20 0.61
TDP1 Q9NUW8 1/20 0.61
L3MBTL1 Q9Y468 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25334320 1.00 ALDH1A1 (0.79) ALDH1A1SMN1; SMN2LMNARGS12NPSR1
SCHEMBL25335686 0.85 RAB9A (0.69) ALDH1A1SMN1; SMN2LMNARGS12NPSR1
SCHEMBL13977439 0.84 RGS12 (0.84) ALDH1A1SMN1; SMN2LMNARGS12NPSR1
SCHEMBL4205396 0.78 ALDH1A1 (0.85) ALDH1A1NPSR1HSD17B10MAPTKDM4E
SCHEMBL25337471 0.76 ALDH1A1 (0.64) ALDH1A1SMN1; SMN2LMNAHSD17B10MAPT
SCHEMBL25335765 0.75 ADRB2 (0.76) ALDH1A1SMN1; SMN2LMNAHSD17B10KDM4E
SCHEMBL15983653 0.75 LMNA (0.66) ALDH1A1SMN1; SMN2LMNANPSR1HSD17B10
SCHEMBL4209017 0.75 POLB (0.80) ALDH1A1LMNAHSD17B10MAPTKDM4E
SCHEMBL2021735 0.74 SMN1; SMN2 (1.00) ALDH1A1SMN1; SMN2LMNAHSD17B10MAPT
SCHEMBL15983538 0.74 ALDH1A1 (0.77) ALDH1A1LMNARGS12HSD17B10KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12564547-B2 Compositions, formulations, and methods for skin treatment ODDITY LABS, LLC (US) 2026-03-03 US disclosed
US-20230240960-A1 COMPOSITIONS, FORMULATIONS, AND METHODS FOR SKIN TREATMENT ODDITY LABS, LLC 2023-08-03 US disclosed
US-20230240960-A1 COMPOSITIONS, FORMULATIONS, AND METHODS FOR SKIN TREATMENT ODDITY LABS, LLC 2023-08-03 US disclosed
US-20230240960-A1 COMPOSITIONS, FORMULATIONS, AND METHODS FOR SKIN TREATMENT ODDITY LABS, LLC 2023-08-03 US disclosed
WO-2023133240-A1 COMPOSITIONS, FORMULATIONS, AND METHODS FOR SKIN TREATMENT REVELA, INC. (US) 2023-07-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230240960-A1 COMPOSITIONS, FORMULATIONS, AND METHODS FOR SKIN TREATMENT CUTA, COL14A1, DSG1 ALDH1A1 3302/4885SMN1; SMN2 696/4885LMNA 44/4885
US-12564547-B2 Compositions, formulations, and methods for skin treatment MCOLN1, H1-0, APOL1 ALDH1A1 1590/4885SMN1; SMN2 1578/4885LMNA 576/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.