Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.31 |
| ▸ | FABP3 | P05413 | 1/20 | 0.30 |
| ▸ | FABP4 | P15090 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5583459 | 0.75 | GABRA1 (0.34) | GABRA1GABRB2FABP3FABP4 | |
| Hydrochloric Acid SCHEMBL27463390 | 0.75 | GABRA1 (0.34) | GABRA1GABRB2FABP3FABP4 | |
| Hydrochloric Acid SCHEMBL9421533 | 0.75 | GABRA1 (0.34) | GABRA1GABRB2FABP3FABP4 | |
| Hydrochloric Acid SCHEMBL7569382 | 0.75 | TGFBR1 (0.32) | — | |
| Hydrochloric Acid SCHEMBL2534898 | 0.75 | GABRA1 (0.32) | GABRA1GABRB2FABP3FABP4 | |
| Hydrochloric Acid SCHEMBL27478549 | 0.74 | FABP4 (0.33) | GABRA1GABRB2FABP3FABP4 | |
| Hydrochloric Acid SCHEMBL1685534 | 0.74 | GABRA1 (0.33) | GABRA1GABRB2FABP3FABP4 | |
| Hydrochloric Acid SCHEMBL29612295 | 0.74 | GABRA1 (0.33) | GABRA1GABRB2FABP3FABP4 | |
| Hydrochloric Acid SCHEMBL385357 | 0.73 | GABRA1 (0.31) | GABRA1GABRB2FABP3FABP4 | |
| SCHEMBL8506274 | 0.73 | GABRA1 (0.35) | GABRA1GABRB2FABP3FABP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5770752-A | Process for reducing the concentration of by-products in product mixtures | TARGOR GMBH (DE) | 1998-06-23 | — | — | US | disclosed |