Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 3/20 | 0.44 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | YWHAG | P61981 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | DRD3 | P35462 | 2/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8553051 | 0.86 | HTR6 (0.45) | HTR6DRD2DRD3DRD1HTR2A | |
| SCHEMBL30798758 | 0.81 | HPGD (0.45) | KDM4EMEN1MAPTTHRBALOX15 | |
| SCHEMBL30798658 | 0.80 | ACVR1 (0.45) | ACVR1MAPT | |
| SCHEMBL29960848 | 0.79 | ACVR1 (0.39) | HTR6ACVR1KDM4EMEN1MAPT | |
| Bromide SCHEMBL7972748 | 0.79 | KDR (0.47) | HTR6ACVR1KDM4EMEN1MAPT | |
| Ammonia Solution, Strong SCHEMBL29115506 | 0.78 | ACVR1 (0.38) | HTR6ACVR1KDM4EMEN1MAPT | |
| SCHEMBL30542904 | 0.78 | ACVR1 (0.38) | HTR6ACVR1KDM4EMEN1MAPT | |
| SCHEMBL27675711 | 0.78 | ADRB1 (0.49) | HTR6ACVR1KDM4EMEN1MAPT | |
| SCHEMBL25232509 | 0.77 | ALDH1A1 (0.45) | HTR6KDM4EMAPTADRB1 | |
| SCHEMBL20076208 | 0.77 | HTR6 (0.46) | HTR6KDM4EHSD17B10HTTHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240116885-A1 | BENZOTHIAZOLE AND QUINOLINE DERIVATIVES AND THEIR USE | SHANGHAI YAO YUAN BIOTECHNOLOGY CO., LTD. (CN) | 2024-04-11 | — | — | US | disclosed |
| EP-4222151-A1 | ALPHA PROTEIN KINASE 1 INHIBITORS AND METHODS OF USE | Shanghai Yao Yuan Biotechnology Co., Ltd. (CN) | 2023-08-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240116885-A1 | BENZOTHIAZOLE AND QUINOLINE DERIVATIVES AND THEIR USE | PHKA1, PHKA2, CSNK1A1 | HTR6 4100/4885ACVR1 1127/4885KDM4E 2525/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.