Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACVR1 | Q04771 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 6/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.36 |
| ▸ | TTR | P02766 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8256371 | 0.85 | ALDH1A1 (0.43) | ACVR1ALDH1A1LMNAHTR2CMAPT | |
| SCHEMBL16600110 | 0.82 | BTK (0.42) | ACVR1ALDH1A1LMNAPARP1 | |
| SCHEMBL25366356 | 0.80 | HTR6 (0.44) | ACVR1MAPT | |
| SCHEMBL16599760 | 0.76 | ADRB1 (0.43) | ACVR1SCN9A | |
| SCHEMBL3633976 | 0.76 | ACVR1 (0.62) | ACVR1ALDH1A1HTR2CPARP1MAPT | |
| Hydrochloric Acid SCHEMBL27825221 | 0.75 | ACVR1 (0.61) | ACVR1ALDH1A1HTR2CPARP1MAPT | |
| SCHEMBL18171738 | 0.73 | ACVR1 (0.45) | ACVR1HTR2CTGFBR1 | |
| SCHEMBL30311470 | 0.72 | ALB (0.47) | ALDH1A1LMNATTR | |
| Bromide SCHEMBL7972748 | 0.72 | KDR (0.47) | ACVR1ALDH1A1LMNAPARP1MAPT | |
| SCHEMBL30518913 | 0.71 | CHRNB2 (0.48) | ACVR1ALDH1A1PARP1TGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240116885-A1 | BENZOTHIAZOLE AND QUINOLINE DERIVATIVES AND THEIR USE | SHANGHAI YAO YUAN BIOTECHNOLOGY CO., LTD. (CN) | 2024-04-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240116885-A1 | BENZOTHIAZOLE AND QUINOLINE DERIVATIVES AND THEIR USE | PHKA1, PHKA2, CSNK1A1 | ACVR1 1127/4885ALDH1A1 1445/4885LMNA 894/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.