SCHEMBL2536751

SCHEMBL2536751

CC=[Ti](C1C=Cc2ccccc21)C1C=Cc2ccccc21

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 2/20 0.34
HTR6 P50406 1/20 0.34
SIGMAR1 Q99720 6/20 0.32
KDM4E B2RXH2 2/20 0.32
BRD4 O60885 1/20 0.32
CCL2 P13500 1/20 0.32
LMNA P02545 1/20 0.32
TP53 P04637 1/20 0.32
CHRM2 P08172 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2D6 P10635 1/20 0.32
CHRM1 P11229 1/20 0.32
DRD2 P14416 1/20 0.32
ADRA2B P18089 1/20 0.32
ADRA2C P18825 1/20 0.32
NFKB1 P19838 1/20 0.32
CHRM3 P20309 1/20 0.32
SLC6A2 P23975 1/20 0.32
HTR2C P28335 1/20 0.32
ADRA1A P35348 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methyl Alcohol SCHEMBL8155137 0.96 HTR6 (0.33) HTR2AHTR6SIGMAR1KDM4EBRD4
SCHEMBL7029036 0.89 SIGMAR1 (0.38) HTR2AHTR6SIGMAR1KCNH2MEN1
SCHEMBL8750712 0.87 GPR3 (0.31) HTR2AKDM4ELMNATP53CHRM2
Methyl Alcohol SCHEMBL8155481 0.84 CYP2D6 (0.31) CYP2D6
SCHEMBL8384029 0.80 SIGMAR1 (0.37) HTR2AHTR6SIGMAR1KDM4ELMNA
SCHEMBL30019252 0.78 HTR2A (0.38) HTR2AHTR6SIGMAR1KDM4EBRD4
SCHEMBL6566244 0.78 HTR2A (0.38) HTR2AHTR6SIGMAR1KDM4EBRD4
SCHEMBL8078360 0.78 HTR2A (0.38) HTR2AHTR6SIGMAR1KDM4EBRD4
SCHEMBL8204113 0.77 HTR2A (0.38) HTR2AHTR6SIGMAR1KDM4EBRD4
SCHEMBL5183873 0.74 HTR2A (0.38) HTR2AHTR6SIGMAR1KDM4EBRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090156763-A1 Process for manufacturing a thermoplastic elastomeric material PIRELLI & C. S.P.A. (IT) 2009-06-18 US claimed
EP-1919972-A1 PROCESS FOR MANUFACTURING A THERMOPLASTIC ELASTOMERIC MATERIAL Pirelli & C. S.p.A. (IT) 2008-05-14 EP claimed
WO-2007025556-A1 PROCESS FOR MANUFACTURING A THERMOPLASTIC ELASTOMERIC MATERIAL PIRELLI & C. S.P.A. (IT) 2007-03-08 WO claimed
US-8373011-B2 Used in a base oil of lubricant having good low temperature fluidity, low evaporativity, and thermal stability and oxidation stability IDEMITSU KOSAN CO., LTD. (JP) 2013-02-12 US disclosed
US-8044144-B2 Resin composition, transparent film or sheet having elasticity recovering property, and wrap film PRIME POLYMER CO., LTD. (JP) 2011-10-25 US disclosed
US-7569713-B2 hydrogenation to prepare a bridged bis(indenyl) hydrogenated metallocene catalyst; use as polymerization catalyst in olefin polymerization to produce stereoregular polyethylene, polypropylene, or ethylene-propylene copolymer TOTAL PETROCHEMICALS RESEARCH FELUY (BE) 2009-08-04 US disclosed
US-20090156763-A1 Process for manufacturing a thermoplastic elastomeric material PIRELLI & C. S.P.A. (IT) 2009-06-18 US disclosed
EP-0945471-B1 CATALYSTS FOR THE POLYMERIZATION OF OLEFINS, PROCESS FOR THE PRODUCTION OF OLEFIN POLYMERS, AND PROCESSES FOR THE PRODUCTION OF STYRENE POLYMERS IDEMITSU KOSAN CO (JP) 2009-05-13 EP disclosed
US-20090012238-A1 RESIN COMPOSITION, TRANSPARENT FILM OR SHEET HAVING ELASTICITY RECOVERING PROPERTY, AND WRAP FILM PRIME POLYMER CO., LTD (JP) 2009-01-08 US disclosed
US-20080146469-A1 Process for producing saturated aliphatic hydrocarbon compound, and lubricant composition IDEMITSU KOSAN CO., LTD. (JP) 2008-06-19 US disclosed
EP-1919972-A1 PROCESS FOR MANUFACTURING A THERMOPLASTIC ELASTOMERIC MATERIAL Pirelli & C. S.p.A. (IT) 2008-05-14 EP disclosed
EP-0984016-A1 ALUMINUM COMPOUND AND PROCESS FOR PRODUCING THE SAME, CATALYST FOR OLEFIN POLYMER PRODUCTION, AND PROCESS FOR PRODUCING OLEFIN POLYMER IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2000-03-08 EP disclosed
EP-0945471-A1 CATALYSTS FOR THE POLYMERIZATION OF OLEFINS, PROCESS FOR THE PRODUCTION OF OLEFIN POLYMERS, AND PROCESSES FOR THE PRODUCTION OF STYRENE POLYMERS IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1999-09-29 EP disclosed
US-5424378-A Catalyzing in the presence of a mixture comprising an alkyl-sulfonate cyclopentadienyl titanium or zirconium compound and an aluminoxane MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1995-06-13 US disclosed
US-5412128-A Catalyst for olefin polymerization, process for the polymerization of olefin, and transition metal compound employable for the catalyst MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1995-05-02 US disclosed
US-5409874-A Containing transition metal compound having cyclopentadienyl skeleton and sulfonate group, aluminoxane or benzene insoluble organoaluminum compound MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1995-04-25 US disclosed
EP-0412750-B1 Production of alpha-olefin polymers MITSUBISHI PETROCHEMICAL CO (JP) 1995-02-15 EP disclosed
US-5191027-A COMPOSITION COMPRISING AN EPOXY COMPOUND DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1993-03-02 US disclosed
EP-0519746-A1 Catalyst for olefin polymerization, process for the polymerization of olefin, and transition metal compound employable for the catalyst MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1992-12-23 EP disclosed
US-4952540-A CATALYST FOR POLYMERIZATION OF OLEFINS MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1990-08-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080146469-A1 Process for producing saturated aliphatic hydrocarbon compound, and lubricant composition ALOX15, ALOX12, ALOX15B HTR2A 411/4885HTR6 435/4885SIGMAR1 489/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.