SCHEMBL25399370

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL25397941	0.88	ALDH1A1 (0.48)	ALDH1A1MAPTKDM4EPOLBSMN1; SMN2
	SCHEMBL25399154	0.83	ALDH1A1 (0.47)	ALDH1A1MAPTKDM4EPOLBNLRP3
	SCHEMBL5009319	0.81	NLRP3 (0.50)	ALDH1A1RIPK1KDM4EPOLBNLRP3
	SCHEMBL7644966	0.78	ALDH1A1 (0.49)	ALDH1A1MAPTKDM4ESMN1; SMN2KMT2A
	SCHEMBL27953552	0.77	AKR1B1 (0.50)	ALDH1A1MAPTSMN1; SMN2KMT2AMEN1
	SCHEMBL25400597	0.77	ALDH1A1 (0.47)	ALDH1A1MAPTRIPK1KDM4EPOLB
	SCHEMBL6835387	0.77	KMT2A (0.56)	ALDH1A1MAPTKDM4ESMN1; SMN2KMT2A
	SCHEMBL4697641	0.76	CASP1 (0.54)	ALDH1A1MAPTKDM4EKMT2AMEN1
	SCHEMBL29665250	0.76	CASP1 (0.54)	ALDH1A1MAPTKDM4EKMT2AMEN1
	SCHEMBL25397875	0.75	POLQ (0.51)	ALDH1A1MAPTKDM4EKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.