Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.70 |
| ▸ | NPC1 | O15118 | 9/20 | 0.70 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.64 |
| ▸ | WNT3A | P56704 | 2/20 | 0.64 |
| ▸ | HPGD | P15428 | 5/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 3/20 | 0.54 |
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2540650 | 0.83 | ATM (0.61) | RAB9ANPC1CTNNB1WNT3AHPGD | |
| SCHEMBL2545038 | 0.82 | STAT3 (0.61) | RAB9ANPC1ALDH1A1MAPTLMNA | |
| SCHEMBL10027736 | 0.78 | CTNNB1 (1.00) | RAB9ANPC1CTNNB1WNT3AHPGD | |
| SCHEMBL15675427 | 0.77 | ALDH1A1 (0.59) | RAB9ANPC1ALDH1A1KDM4EMAPT | |
| SCHEMBL2541632 | 0.77 | PAX8 (0.65) | RAB9ANPC1CTNNB1WNT3AALDH1A1 | |
| SCHEMBL2541643 | 0.77 | ENPP2 (0.59) | RAB9ANPC1HPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL2537406 | 0.76 | KMT2A (0.59) | RAB9ANPC1ALDH1A1TP53L3MBTL1 | |
| SCHEMBL2542303 | 0.76 | KMT2A (0.59) | RAB9ANPC1ALDH1A1POLBKDM4E | |
| SCHEMBL4828375 | 0.76 | NPC1 (0.70) | RAB9ANPC1CTNNB1WNT3AHPGD | |
| SCHEMBL1089246 | 0.76 | RECQL (0.60) | RAB9ANPC1ALDH1A1SMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8044245-B2 | Method for the preparation of optically active 2-sulfonyloxy-1-phenylethanol derivatives | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2011-10-25 | — | — | US | disclosed |
| US-20100063317-A1 | METHOD FOR THE PREPARATION OF OPTICALLY ACTIVE 2-SULFONYLOXY-1-PHENYLETHANOL DERIVATIVES | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2010-03-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100063317-A1 | METHOD FOR THE PREPARATION OF OPTICALLY ACTIVE 2-SULFONYLOXY-1-PHENYLETHANOL DERIVATIVES | FOXO1, ENO1, SULT1A1 | RAB9A 2562/4885NPC1 1514/4885CTNNB1 373/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.