Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.56 |
| ▸ | MAPT | P10636 | 6/20 | 0.56 |
| ▸ | NPC1 | O15118 | 5/20 | 0.56 |
| ▸ | RAB9A | P51151 | 5/20 | 0.56 |
| ▸ | TP53 | P04637 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | GLA | P06280 | 2/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
| ▸ | CASP3 | P42574 | 1/20 | 0.56 |
| ▸ | CCR6 | P51684 | 1/20 | 0.56 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.56 |
| ▸ | RELA | Q04206 | 1/20 | 0.56 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.56 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.56 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.51 |
| ▸ | MEN1 | O00255 | 5/20 | 0.51 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15246754 | 0.82 | RAB9A (0.61) | SMN1; SMN2MAPTNPC1RAB9ATP53 | |
| SCHEMBL861076 | 0.73 | ALDH1A1 (0.49) | SMN1; SMN2MAPTNPC1RAB9ATP53 | |
| SCHEMBL1801245 | 0.72 | RAB9A (0.49) | SMN1; SMN2MAPTNPC1RAB9ATP53 | |
| SCHEMBL21295 | 0.72 | KMT2A (0.70) | SMN1; SMN2MAPTNPC1RAB9ATP53 | |
| SCHEMBL29668346 | 0.72 | KMT2A (0.70) | SMN1; SMN2MAPTNPC1RAB9ATP53 | |
| SCHEMBL2252028 | 0.72 | SMN1; SMN2 (1.00) | SMN1; SMN2MAPTNPC1RAB9ATP53 | |
| SCHEMBL15246728 | 0.70 | MEN1 (0.59) | SMN1; SMN2MAPTNPC1RAB9ATP53 | |
| SCHEMBL16387688 | 0.70 | MAPT (0.62) | SMN1; SMN2MAPTNPC1RAB9ATP53 | |
| SCHEMBL12779078 | 0.69 | BACE1 (0.63) | SMN1; SMN2MAPTNPC1RAB9ATP53 | |
| SCHEMBL5291860 | 0.68 | RAB9A (1.00) | SMN1; SMN2MAPTNPC1RAB9ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230247997-A1 | NEMATICIDE COMPOUNDS, COMPOSITIONS, AND METHODS OF THEIR MAKING AND USE | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. | 2023-08-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230247997-A1 | NEMATICIDE COMPOUNDS, COMPOSITIONS, AND METHODS OF THEIR MAKING AND USE | ACHE, NISCH, CASP7 | SMN1; SMN2 388/4885MAPT 2976/4885NPC1 424/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.