Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.97 |
| ▸ | THRB | P10828 | 10/20 | 0.97 |
| ▸ | MAPT | P10636 | 8/20 | 0.97 |
| ▸ | TSHR | P16473 | 3/20 | 0.97 |
| ▸ | LMNA | P02545 | 7/20 | 0.90 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.90 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.90 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.90 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.90 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.90 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.90 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.90 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.90 |
| ▸ | DRD4 | P21917 | 1/20 | 0.90 |
| ▸ | ACHE | P22303 | 1/20 | 0.90 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.90 |
| ▸ | HRH2 | P25021 | 1/20 | 0.90 |
| ▸ | HTR2A | P28223 | 1/20 | 0.90 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.90 |
| ▸ | HRH1 | P35367 | 1/20 | 0.90 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29378842 | 1.00 | ALDH1A1 (0.97) | ALDH1A1THRBMAPTTSHRLMNA | |
| Propipocaine SCHEMBL4457156 | 0.99 | ALDH1A1 (1.00) | ALDH1A1THRBMAPTTSHRLMNA | |
| Propipocaine SCHEMBL1650998 | 0.97 | ALDH1A1 (0.93) | ALDH1A1THRBMAPTTSHRLMNA | |
| SCHEMBL29766083 | 0.95 | THRB (1.00) | ALDH1A1THRBMAPTTSHRLMNA | |
| Dyclonine SCHEMBL25773 | 0.95 | THRB (1.00) | ALDH1A1THRBMAPTTSHRLMNA | |
| Dyclonine SCHEMBL317219 | 0.93 | THRB (1.00) | ALDH1A1THRBMAPTTSHRLMNA | |
| Dyclonine SCHEMBL1649948 | 0.92 | THRB (0.95) | ALDH1A1THRBMAPTTSHRLMNA | |
| SCHEMBL9320014 | 0.91 | THRB (1.00) | ALDH1A1THRBMAPTTSHRLMNA | |
| SCHEMBL9319585 | 0.91 | THRB (1.00) | ALDH1A1THRBMAPTTSHRLMNA | |
| SCHEMBL9320006 | 0.91 | THRB (1.00) | ALDH1A1THRBMAPTTSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1878 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260115156-A1 | INJECTABLE COMPOSITION INCLUDING HYDROGEL CONTAINING ANESTHETIC AGENT | UNIV KOREA RES & BUS FOUND (KR) | 2026-04-30 | — | — | US | claimed |
| WO-2025235864-A1 | COATED NEEDLE ADMINISTRATION SYSTEMS | EVOLUS, INC. (US) | 2025-11-13 | — | — | WO | claimed |
| US-12419619-B2 | Aspiration device | YALE UNIVERSITY (US) | 2025-09-23 | — | — | US | claimed |
| EP-4578441-A1 | TREATMENT OF LOCALIZED PAIN | PlantTec Medical GmbH (DE) | 2025-07-02 | — | — | EP | claimed |
| US-12329856-B2 | Crosslinked hyaluronic acid composition with local anesthetics | BIOPOLIMERI S.R.L. (IT) | 2025-06-17 | — | — | US | claimed |
| US-20250186364-A1 | COMBINATION OF ANTISPASMODIC AND ANESTHETIC AGENTS FOR TOPICAL PRODUCTS AND THEIR METHOD OF USE | PRIMA INNOVATIONS, LLC | 2025-06-12 | — | — | US | claimed |
| EP-4362994-B1 | CROSSLINKED HYALURONIC ACID COMPOSITION WITH LOCAL ANESTHETICS | BIOPOLIMERI S R L (IT) | 2025-03-12 | — | — | EP | claimed |
| EP-3703802-B9 | NASAL DELIVERY DEVICES AND METHODS OF USE THEREOF | CLEXIO BIOSCIENCES LTD (IL) | 2024-12-04 | — | — | EP | claimed |
| EP-3703802-B1 | NASAL DELIVERY DEVICES AND METHODS OF USE THEREOF | CLEXIO BIOSCIENCES LTD (IL) | 2024-10-16 | — | — | EP | claimed |
| US-20240293311-A1 | CROSSLINKED HYALURONIC ACID COMPOSITION WITH LOCAL ANESTHETICS | BIOPOLIMERI S.R.L. (IT) | 2024-09-05 | — | — | US | claimed |
| WO-2001043733-A2 | COMPOSITIONS, KITS, APPARATUS, AND METHODS FOR INHIBITING CEPHALIC INFLAMMATION | LEVIN BRUCE H (US) | 2001-06-21 | — | — | WO | claimed |
| EP-1073470-A1 | PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS | INPHARMA S.A. (CH) | 2001-02-07 | — | — | EP | claimed |
| WO-2000048636-A1 | PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS | INPHARMA S.A. (CH) | 2000-08-24 | — | — | WO | claimed |
| EP-1027015-A1 | CONTROLLED RELEASE OF PHARMACEUTICALS IN THE ANTERIOR CHAMBER OF THE EYE | Galin, Miles A. (US) | 2000-08-16 | — | — | EP | claimed |
| US-5972326-A | Controlled release of pharmaceuticals in the anterior chamber of the eye | IOLTECH (FR) | 1999-10-26 | — | — | US | claimed |
| WO-1998041171-A1 | CONTROLLED RELEASE OF PHARMACEUTICALS IN THE ANTERIOR CHAMBER OF THE EYE | GALIN MILES A (US) | 1998-09-24 | — | — | WO | claimed |
| EP-0383481-B1 | Anesthetic oral compositions | RICHARDSON VICKS INC (US) | 1994-01-19 | — | — | EP | claimed |
| EP-0383481-A2 | Anesthetic oral compositions | Richardson-Vicks, Inc. (US) | 1990-08-22 | — | — | EP | claimed |
| US-4931473-A | BETA-AMINO PROPIOPHENONES WITH SACCHARIN STABILIZER; THROAT LOZENGES | RICHARDSON-VICKS INC. (US) | 1990-06-05 | — | — | US | claimed |
| US-4333941-A | Inhibition of enveloped viruses with phenyl ketones | THE DOW CHEMICAL COMPANY (US) | 1982-06-08 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12329856-B2 | Crosslinked hyaluronic acid composition with local anesthetics | CD44, HCAR3, HCAR2 | ALDH1A1 674/4885THRB 3166/4885MAPT 3195/4885 |
| US-20260115156-A1 | INJECTABLE COMPOSITION INCLUDING HYDROGEL CONTAINING ANESTHETIC AGENT | CES2, DAGLA, ACHE | ALDH1A1 1610/4885THRB 1366/4885MAPT 2193/4885 |
| US-20240293311-A1 | CROSSLINKED HYALURONIC ACID COMPOSITION WITH LOCAL ANESTHETICS | CD44, HCAR3, HCAR2 | ALDH1A1 674/4885THRB 3166/4885MAPT 3195/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.