SCHEMBL25446151

SCHEMBL25446151

Cc1cc(C)c(-c2cc(C(C)C)c(C(C)C)c[n+]2C)cc1-c1ccccc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 1/20 0.35
KMT2A Q03164 1/20 0.34
HTT P42858 4/20 0.32
ALDH1A1 P00352 3/20 0.32
GAA P10253 1/20 0.32
HSD17B10 Q99714 1/20 0.32
DHFR P00374 1/20 0.31
CA2 P00918 3/20 0.31
CA1 P00915 2/20 0.31
CA9 Q16790 2/20 0.31
KDM4E B2RXH2 2/20 0.31
SMN1; SMN2 Q16637 2/20 0.31
CA12 O43570 1/20 0.31
LMNA P02545 1/20 0.31
MAPT P10636 1/20 0.31
NR2F2 P24468 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
CYP2A6 P11509 1/20 0.30
CYP2B6 P20813 1/20 0.30
MCOLN3 Q8TDD5 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25446154 0.93 ESR2 (0.36) ESR2KMT2AHTTALDH1A1DHFR
SCHEMBL25446167 0.91 ESR2 (0.35) ESR2KMT2AHTTALDH1A1DHFR
SCHEMBL25446098 0.82 ESR2 (0.41) ESR2KMT2AHTTALDH1A1DHFR
SCHEMBL25447415 0.80 ESR2 (0.40) ESR2KMT2AHTTALDH1A1DHFR
SCHEMBL25445897 0.80 ALDH1A1 (0.32) KMT2AHTTALDH1A1GAAHSD17B10
SCHEMBL25976867 0.80 LDHA (0.35) DHFRLMNA
SCHEMBL25976376 0.79 HTT (0.34) KMT2AHTTKDM4ESMN1; SMN2LMNA
SCHEMBL25452061 0.78 NPC1 (0.36) ESR2KMT2AALDH1A1CA2CA1
SCHEMBL25976443 0.77 METAP2 (0.39) ESR2HTTDHFRKDM4ESMN1; SMN2
SCHEMBL25446126 0.77 ESR2 (0.33) ESR2HTTSMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240224783-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-07-04 US disclosed
US-20240074301-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-02-29 US disclosed
EP-4329463-A2 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2024-02-28 EP disclosed
EP-4001287-B1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORP (US) 2024-01-17 EP disclosed
US-11864458-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2024-01-02 US disclosed
US-11839141-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-12-05 US disclosed
EP-3858945-B1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORP (US) 2023-11-29 EP disclosed
US-11827651-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-11-28 US disclosed
US-20230371358-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-16 US disclosed
US-20230365606-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-16 US disclosed
US-20230151039-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-05-18 US disclosed
US-20230157154-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-05-18 US disclosed
EP-3771717-B1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORP (US) 2023-05-17 EP disclosed
US-20230147066-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-05-11 US disclosed
US-20230142498-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-05-11 US disclosed
US-20230146148-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-05-11 US disclosed
US-20230143449-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-05-11 US disclosed
US-11647667-B2 Organic electroluminescent compounds and organic light emitting devices using the same UNIVERSAL DISPLAY CORPORATION (US) 2023-05-09 US disclosed
US-11639363-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-05-02 US disclosed
US-20230130017-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-04-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (16 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230157154-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES LIFR, SOD1, GLRA3 ESR2 58/4885KMT2A 2384/4885HTT 4331/4885
US-20230146148-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, ICOSLG ESR2 238/4885KMT2A 3770/4885HTT 3497/4885
US-11647667-B2 Organic electroluminescent compounds and organic light emitting devices using the same OCIAD1, OCIAD2, ODC1 ESR2 480/4885KMT2A 2151/4885HTT 1214/4885
US-20230130017-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, SSB ESR2 76/4885KMT2A 2753/4885HTT 4235/4885
US-11839141-B2 Organic electroluminescent materials and devices OSBP, OCIAD1, OCIAD2 ESR2 723/4885KMT2A 4141/4885HTT 2484/4885
US-11864458-B2 Organic electroluminescent materials and devices RAP1A, L1CAM, SOD1 ESR2 220/4885KMT2A 1364/4885HTT 3280/4885
US-20230147066-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, SSB, MCOLN3 ESR2 248/4885KMT2A 1752/4885HTT 3899/4885
US-20230143449-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, OXER1 ESR2 80/4885KMT2A 609/4885HTT 3582/4885
US-20230142498-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, LEF1 ESR2 142/4885KMT2A 3135/4885HTT 4389/4885
US-20240074301-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES ICOSLG, OCIAD2, OSBP ESR2 295/4885KMT2A 4312/4885HTT 2222/4885
US-20240224783-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, ICOSLG ESR2 105/4885KMT2A 3450/4885HTT 937/4885
US-11639363-B2 Organic electroluminescent materials and devices LEF1, L1CAM, SSB ESR2 122/4885KMT2A 2041/4885HTT 3919/4885
US-20230371358-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES LIFR, SOD1, ROS1 ESR2 34/4885KMT2A 2331/4885HTT 4274/4885
US-20230365606-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OXER1, OPRD1, OXSR1 ESR2 54/4885KMT2A 3396/4885HTT 4568/4885
US-11827651-B2 Organic electroluminescent materials and devices SSB, L1CAM, LEF1 ESR2 39/4885KMT2A 1474/4885HTT 1268/4885
US-20230151039-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES RPS4X, SOD1, CNKSR1 ESR2 438/4885KMT2A 2545/4885HTT 4478/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.