SCHEMBL25446154

SCHEMBL25446154

Cc1cc(C)c(-c2cc(C(C)C)c(C)c[n+]2C)cc1-c1ccccc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 1/20 0.36
KMT2A Q03164 1/20 0.35
DHFR P00374 1/20 0.32
HTT P42858 3/20 0.32
CA2 P00918 3/20 0.31
KDM4E B2RXH2 2/20 0.31
SMN1; SMN2 Q16637 2/20 0.31
CA1 P00915 2/20 0.31
CA9 Q16790 2/20 0.31
CA12 O43570 1/20 0.31
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.31
MAPT P10636 1/20 0.31
NR2F2 P24468 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
CYP2A6 P11509 1/20 0.31
CYP2B6 P20813 1/20 0.31
HSP90AA1 P07900 1/20 0.31
NPC1 O15118 1/20 0.31
RAB9A P51151 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25446151 0.93 ESR2 (0.35) ESR2KMT2ADHFRHTTCA2
SCHEMBL25446167 0.90 ESR2 (0.35) ESR2KMT2ADHFRHTTCA2
SCHEMBL25976867 0.87 LDHA (0.35) DHFRLMNA
SCHEMBL25446098 0.86 ESR2 (0.41) ESR2KMT2ADHFRHTTKDM4E
SCHEMBL25976376 0.86 HTT (0.34) KMT2AHTTKDM4ESMN1; SMN2LMNA
SCHEMBL25447415 0.84 ESR2 (0.40) ESR2KMT2ADHFRHTTKDM4E
SCHEMBL25517571 0.81 LMNA (0.32) KMT2ADHFRHTTCA2KDM4E
SCHEMBL25446102 0.81 ESR2 (0.33) ESR2HTTSMN1; SMN2LMNARAB9A
SCHEMBL25976745 0.80 AR (0.35) CA2CA1CA9CA12ALDH1A1
SCHEMBL25446066 0.80 ESR2 (0.41) ESR2KMT2ADHFRHTTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240224783-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-07-04 US disclosed
US-20240074301-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-02-29 US disclosed
EP-4329463-A2 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2024-02-28 EP disclosed
EP-4001287-B1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORP (US) 2024-01-17 EP disclosed
US-11864458-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2024-01-02 US disclosed
US-11839141-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-12-05 US disclosed
EP-3858945-B1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORP (US) 2023-11-29 EP disclosed
US-11827651-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-11-28 US disclosed
US-20230371358-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-16 US disclosed
US-20230365606-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-16 US disclosed
US-20230165134-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-05-25 US disclosed
US-20230151039-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-05-18 US disclosed
US-20230157154-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-05-18 US disclosed
EP-3771717-B1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORP (US) 2023-05-17 EP disclosed
US-20230147066-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-05-11 US disclosed
US-20230146148-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-05-11 US disclosed
US-20230143449-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-05-11 US disclosed
US-20230142498-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-05-11 US disclosed
US-11647667-B2 Organic electroluminescent compounds and organic light emitting devices using the same UNIVERSAL DISPLAY CORPORATION (US) 2023-05-09 US disclosed
US-20230130017-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-04-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (16 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230157154-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES LIFR, SOD1, GLRA3 ESR2 58/4885KMT2A 2384/4885DHFR 2563/4885
US-20230146148-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, ICOSLG ESR2 238/4885KMT2A 3770/4885DHFR 3346/4885
US-11647667-B2 Organic electroluminescent compounds and organic light emitting devices using the same OCIAD1, OCIAD2, ODC1 ESR2 480/4885KMT2A 2151/4885DHFR 1639/4885
US-20230165134-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, TPO ESR2 776/4885KMT2A 1926/4885DHFR 3603/4885
US-20230130017-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, SSB ESR2 76/4885KMT2A 2753/4885DHFR 3795/4885
US-11839141-B2 Organic electroluminescent materials and devices OSBP, OCIAD1, OCIAD2 ESR2 723/4885KMT2A 4141/4885DHFR 4001/4885
US-11864458-B2 Organic electroluminescent materials and devices RAP1A, L1CAM, SOD1 ESR2 220/4885KMT2A 1364/4885DHFR 2249/4885
US-20230147066-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, SSB, MCOLN3 ESR2 248/4885KMT2A 1752/4885DHFR 3974/4885
US-20230143449-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, OXER1 ESR2 80/4885KMT2A 609/4885DHFR 4204/4885
US-20230142498-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, LEF1 ESR2 142/4885KMT2A 3135/4885DHFR 3842/4885
US-20240074301-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES ICOSLG, OCIAD2, OSBP ESR2 295/4885KMT2A 4312/4885DHFR 3558/4885
US-20240224783-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, ICOSLG ESR2 105/4885KMT2A 3450/4885DHFR 3449/4885
US-20230371358-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES LIFR, SOD1, ROS1 ESR2 34/4885KMT2A 2331/4885DHFR 2976/4885
US-20230365606-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OXER1, OPRD1, OXSR1 ESR2 54/4885KMT2A 3396/4885DHFR 4500/4885
US-11827651-B2 Organic electroluminescent materials and devices SSB, L1CAM, LEF1 ESR2 39/4885KMT2A 1474/4885DHFR 2226/4885
US-20230151039-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES RPS4X, SOD1, CNKSR1 ESR2 438/4885KMT2A 2545/4885DHFR 4535/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.