Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of Chloroform. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Chloroform SCHEMBL28063298 | 1.00 | LMNA (0.50) | — | |
| Chloroform SCHEMBL8907442 | 1.00 | LMNA (0.50) | — | |
| Chloroform SCHEMBL28040546 | 1.00 | — | — | |
| Chloroform SCHEMBL27706310 | 1.00 | LMNA (0.50) | — | |
| Chloroform SCHEMBL9617984 | 1.00 | LMNA (0.50) | — | |
| Chloroform SCHEMBL28856156 | 0.94 | — | — | |
| Chloroform SCHEMBL241751 | 0.94 | — | — | |
| Chloroform SCHEMBL4395340 | 0.94 | LMNA (0.44) | — | |
| Chloroform SCHEMBL237266 | 0.94 | — | — | |
| Chloroform SCHEMBL9525441 | 0.94 | LMNA (0.57) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 7910 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115181144-B | Ailanthus altissima triterpene, application and preparation method thereof | 暨南大学 | 2024-06-28 | — | — | CN | claimed |
| WO-2024128835-A1 | NOVEL COMPOUND DERIVED FROM LORANTHUS TANAKAE AND ANTICANCER USE THEREOF | 한국한의학연구원 | 2024-06-20 | — | — | WO | claimed |
| CN-118191291-A | Improved click chemistry-based protein palmitoylation modification detection method | 中国科学院大连化学物理研究所 | 2024-06-14 | — | — | CN | claimed |
| CN-118105358-A | Preparation method of biomimetic mineralized bacterial membrane vesicle and application of biomimetic mineralized bacterial membrane vesicle in targeted antibacterial aspect | 北京化工大学 | 2024-05-31 | — | — | CN | claimed |
| CN-118078902-A | Pharmaceutical composition for acute pancreatitis and preparation and identification methods thereof | 贵州省人民医院 | 2024-05-28 | — | — | CN | claimed |
| WO-2024106740-A1 | COMPOSITION FOR CONTROLLING PHYTOPATHOGENIC FUNGI OR REDUCING MYCOTOXIN, COMPRISING CULTURE SOLUTION OF BACILLUS VELEZENSIS JCK-7158 OR EXTRACT OF STRAIN CULTURE SOLUTION, PREPARATION METHOD THEREFOR, AND METHOD FOR CONTROLLING PHYTOPATHOGENIC FUNGI OR REDUCING MYCOTOXIN | 전남대학교산학협력단 | 2024-05-23 | — | — | WO | claimed |
| CN-117402203-B | Method for extracting and identifying hypolipidemic saponins in garlic residues | 临沂大学 | 2024-05-17 | — | — | CN | claimed |
| CN-117571910-B | Thin-layer identification method of cortex phellodendri serving as medicinal material in Chinese medicinal composition containing Chinese angelica and application of thin-layer identification method | 湖南易能生物医药有限公司 | 2024-05-17 | — | — | CN | claimed |
| CN-117871765-A | Thin-layer identification method of medicinal materials of astragalus membranaceus, rhizoma anemarrhenae and platycodon grandiflorum in traditional Chinese medicine composition containing astragalus membranaceus and application of thin-layer identification method | 湖南易能生物医药有限公司 | 2024-04-12 | — | — | CN | claimed |
| CN-117865888-A | Diterpenoid alkaloid compound in delphinium talnifolia, and preparation method and application thereof | 中国科学院新疆理化技术研究所 | 2024-04-12 | — | — | CN | claimed |
| CN-1042544-A | The extraction method of the principal constituent of Longhairy Antenoron Herb (the pure and mild flavonoid glycoside of triterpene Chinese honey locust) | WANG GANROU (CN) | 1990-05-30 | — | — | CN | claimed |
| US-4875974-A | PECTIN | THE PROCTER & GAMBLE COMPANY (US) | 1989-10-24 | — | — | US | claimed |
| EP-0287158-A2 | Extrusion cooked snack chips | THE PROCTER & GAMBLE COMPANY (US) | 1988-10-19 | — | — | EP | claimed |
| US-4737582-A | PECTIN-CONTAINING, INCORPORATING CATION EXCHANGE GROUPS, FOR DISPOSABLE PRODUCTS | THE PROCTER & GAMBLE COMPANY (US) | 1988-04-12 | — | — | US | claimed |
| EP-0137611-A2 | Absorbent vegetable material and process for making same | THE PROCTER & GAMBLE COMPANY (US) | 1985-04-17 | — | — | EP | claimed |
| EP-0137608-A2 | Absorbent structures comprising vegetable absorbent material and disposable diapers incorporating such structures | THE PROCTER & GAMBLE COMPANY (US) | 1985-04-17 | — | — | EP | claimed |
| US-4415733-A | Ganglioside derivatives, their preparation and their application | SOCIETE ANONYME DITE: INSTITUT MERIEUX (FR) | 1983-11-15 | — | — | US | claimed |
| US-4368195-A | Method for the extraction of silymarin from plants | DR. MADAUS & CO. (DE) | 1983-01-11 | — | — | US | claimed |
| US-4027016-A | Everninomicin antibacterial derivatives, electrochemical method for their manufacture, method for their use as antibacterial agents, and pharmaceutical compositions useful therefor | SCHERING CORPORATION (US) | 1977-05-31 | — | — | US | claimed |
| US-3982325-A | Method of solvent drying | KIMBERLY-CLARK CORPORATION (US) | 1976-09-28 | — | — | US | claimed |