SCHEMBL25454476

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL25454478	0.86	TTR (0.50)	RPS6KA3CHEK1DAPK3RETPDGFRB
	SCHEMBL17614925	0.83	ESR1 (0.46)	LMNACNR2ALOX5
	SCHEMBL24106203	0.81	APP (0.44)	APPTRPV1RPS6KA3CHEK1DAPK3
	SCHEMBL25454479	0.80	ALOX5 (0.43)	CNR2ALOX5
	SCHEMBL23762847	0.76	APP (0.38)	APPTRPV1RPS6KA3CHEK1DAPK3
	SCHEMBL26853190	0.76	APP (0.39)	APPTRPV1LMNAIGF1RCNR2
	SCHEMBL12121971	0.74	PTGS2 (0.52)	CNR2
	SCHEMBL24106132	0.74	APP (0.40)	APPTRPV1LMNAAMY1AIGF1R
	SCHEMBL27280320	0.74	TTR (0.64)	APPTRPV1RPS6KA3TTRLMNA
	SCHEMBL11677802	0.73	CHEK1 (0.39)	RPS6KA3CHEK1DAPK3RETPDGFRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.