Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 20/20 | 0.80 |
| ▸ | TUBB | P07437 | 20/20 | 0.80 |
| ▸ | TUBA3C | P0DPH7 | 20/20 | 0.80 |
| ▸ | TUBA1B | P68363 | 20/20 | 0.80 |
| ▸ | TUBA4A | P68366 | 20/20 | 0.80 |
| ▸ | TUBB4B | P68371 | 20/20 | 0.80 |
| ▸ | TUBB3 | Q13509 | 20/20 | 0.80 |
| ▸ | TUBB2A | Q13885 | 20/20 | 0.80 |
| ▸ | TUBB8 | Q3ZCM7 | 20/20 | 0.80 |
| ▸ | TUBA3E | Q6PEY2 | 20/20 | 0.80 |
| ▸ | TUBA1A | Q71U36 | 20/20 | 0.80 |
| ▸ | TUBA1C | Q9BQE3 | 20/20 | 0.80 |
| ▸ | TUBB6 | Q9BUF5 | 20/20 | 0.80 |
| ▸ | TUBB2B | Q9BVA1 | 20/20 | 0.80 |
| ▸ | TUBB1 | Q9H4B7 | 20/20 | 0.80 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2551209 | 0.89 | TUBB4A (1.00) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL8995335 | 0.77 | ALOX5 (0.56) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL5808205 | 0.73 | TUBB4A (1.00) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL5808169 | 0.70 | TUBB4A (1.00) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL2551998 | 0.70 | TUBB4A (1.00) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL2545689 | 0.69 | TUBB4A (0.71) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL28456102 | 0.68 | TUBB4A (0.72) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL12284987 | 0.66 | TUBB4A (0.76) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL7035552 | 0.65 | PTGS2 (0.56) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL13436536 | 0.65 | MTNR1A (0.71) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011121629-A1 | INDOLIC DERIVATIVES AND USE THEREOF IN MEDICAL FIELD | UNIVERSITA' DEGLI STUDI DL ROMA "LA SAPIENZA" (IT) | 2011-10-06 | — | — | WO | disclosed |
| WO-2011121629-A1 | INDOLIC DERIVATIVES AND USE THEREOF IN MEDICAL FIELD | UNIVERSITA' DEGLI STUDI DL ROMA "LA SAPIENZA" (IT) | 2011-10-06 | — | — | WO | disclosed |