SCHEMBL25463196

SCHEMBL25463196

CCNC(=O)Oc1ccccc1I

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.60
KMT2A Q03164 2/20 0.60
KDM4E B2RXH2 1/20 0.60
MEN1 O00255 1/20 0.60
POLB P06746 1/20 0.60
MAPT P10636 1/20 0.60
THRB P10828 1/20 0.60
BLM P54132 1/20 0.60
L3MBTL1 Q9Y468 1/20 0.60
MGLL Q99685 1/20 0.43
ACHE P22303 3/20 0.41
BCHE P06276 2/20 0.41
FABP7 O15540 1/20 0.41
FABP3 P05413 1/20 0.41
FABP5 Q01469 1/20 0.41
FAAH O00519 1/20 0.40
ALDH1A1 P00352 2/20 0.39
PGR P06401 1/20 0.39
PTGS1 P23219 1/20 0.39
MAPK1 P28482 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29021181 0.84 MGLL (0.57) MGLLALDH1A1NCEH1
SCHEMBL28023340 0.81 GAA (0.58) GAAKMT2AKDM4EMEN1POLB
SCHEMBL25278077 0.81 MAPT (0.58) GAAKMT2AKDM4EMEN1POLB
SCHEMBL25275004 0.81 L3MBTL1 (0.58) GAAKMT2AKDM4EMEN1POLB
SCHEMBL28378813 0.80 NCEH1 (0.56) GAABCHEFAAHALDH1A1NCEH1
SCHEMBL27938524 0.79 FAAH (0.59) GAAKMT2AKDM4EMEN1POLB
SCHEMBL13724306 0.79 KDM4E (0.56) GAAKMT2AKDM4EMEN1POLB
SCHEMBL9813619 0.77 ALDH1A1 (0.69) GAAKMT2AKDM4EMEN1POLB
SCHEMBL9270826 0.77 ALDH1A1 (0.69) GAAKMT2AKDM4EMEN1POLB
SCHEMBL11463950 0.77 CES2 (0.60) GAAKMT2AKDM4EMEN1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11648524-B2 Method for controlling ultrafast chemical reaction using a microfluidic reactor fabricated by high-resolution 3D metal printing technique POSTECH ACADEMY-INDUSTRY FOUNDATION (KR) 2023-05-16 US disclosed
CN-112679447-B Preparation method of polysubstituted thiazole-2 (3H) -ketone compound 甘肃森瀚石油科技有限公司 2022-12-06 CN disclosed
CN-112679447-A Preparation method of polysubstituted thiazole-2 (3H) -ketone compound 兰州大学 2021-04-20 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11648524-B2 Method for controlling ultrafast chemical reaction using a microfluidic reactor fabricated by high-resolution 3D metal printing technique FGR, CYP4F3, CYP4F2 GAA 1867/4885KMT2A 579/4885KDM4E 154/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.