Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCEH1 | Q6PIU2 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | PRNP | P04156 | 5/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | OGG1 | O15527 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | CTSD | P07339 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4539589 | 0.81 | ALDH1A1 (0.60) | NCEH1LMNAALDH1A1KDM4E | |
| SCHEMBL6846901 | 0.81 | OGG1 (0.72) | HPGDSMN1; SMN2LMNAOGG1ALDH1A1 | |
| SCHEMBL2560822 | 0.80 | L3MBTL1 (0.59) | HPGDSMN1; SMN2PRNPRXFP1LMNA | |
| SCHEMBL13209662 | 0.78 | NCEH1 (0.57) | NCEH1HPGDLMNACTSDALDH1A1 | |
| SCHEMBL18494105 | 0.77 | GAA (0.59) | NCEH1ALDH1A1TDP1KCNH2 | |
| SCHEMBL13209884 | 0.77 | NCEH1 (0.56) | NCEH1HPGDLMNACTSDALDH1A1 | |
| SCHEMBL4531027 | 0.77 | CA9 (0.64) | NCEH1HPGDSMN1; SMN2LMNACTSD | |
| SCHEMBL13210145 | 0.77 | NCEH1 (0.56) | NCEH1HPGDSMN1; SMN2LMNACTSD | |
| SCHEMBL29843665 | 0.77 | RAPGEF3 (0.49) | NCEH1HPGDSMN1; SMN2PRNPRXFP1 | |
| SCHEMBL23843604 | 0.77 | RAPGEF3 (0.49) | NCEH1HPGDSMN1; SMN2PRNPRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230150929-A1 | SELECTIVE NON-CYCLIC NUCLEOTIDE ACTIVATORS FOR THE CAMP SENSOR EPAC1 | UNIV TEXAS (US) | 2023-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230150929-A1 | SELECTIVE NON-CYCLIC NUCLEOTIDE ACTIVATORS FOR THE CAMP SENSOR EPAC1 | CREB1, RAPGEF4, ATF4 | NCEH1 1848/4885HPGD 1544/4885SMN1; SMN2 4027/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.