SCHEMBL25465253

SCHEMBL25465253

CCc1cccc(-c2ccc(Oc3[nH]nnc3C(=O)O)cc2)c1

nearest known ligand 0.52

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
BCL2 P10415 1/20 0.52
PTGS2 P35354 1/20 0.45
FGFR1 P11362 1/20 0.41
ABHD6 Q9BV23 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21296942 0.87 ALDH1A1 (0.43) BCL2
SCHEMBL29799129 0.87 ALDH1A1 (0.43) BCL2
SCHEMBL21296966 0.84 ALPL (0.43)
SCHEMBL21296854 0.84 HAO1 (0.44)
SCHEMBL21296929 0.84 PIN1 (0.49)
SCHEMBL29799054 0.82 HAO1 (0.47)
SCHEMBL21312597 0.82 HAO1 (0.47)
SCHEMBL21312624 0.82 HAO1 (0.47)
SCHEMBL24154727 0.82 RXRA (0.52)
SCHEMBL21296954 0.81 PRKAG1 (0.50)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230143491-A1 TRIAZOLE GLYCOLATE OXIDASE INHIBITORS PHOENIX TISSUE REPAIR, INC. 2023-05-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230143491-A1 TRIAZOLE GLYCOLATE OXIDASE INHIBITORS XDH, DUOX1, PNPO BCL2 4223/4885PTGS2 1093/4885FGFR1 657/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.