SCHEMBL25477243

SCHEMBL25477243

CC(C)CCCCCCCCCC(=O)C(C)C

nearest known ligand 0.52

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
KDM4C Q9H3R0 2/20 0.47
KDM4A O75164 1/20 0.47
PHF8 Q9UPP1 1/20 0.47
KDM2A Q9Y2K7 1/20 0.47
LTA4H P09960 1/20 0.44
CA1 P00915 2/20 0.41
LMNA P02545 1/20 0.40
CES2 O00748 1/20 0.40
BLM P54132 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27056807 1.00 KDM4C (0.47) KDM4CKDM4APHF8KDM2ALTA4H
SCHEMBL6726304 1.00 KDM4C (0.47) KDM4CKDM4APHF8KDM2ALTA4H
SCHEMBL5571309 1.00 KDM4C (0.47) KDM4CKDM4APHF8KDM2ALTA4H
SCHEMBL13684770 1.00 KDM4C (0.47) KDM4CKDM4APHF8KDM2ALTA4H
SCHEMBL26203804 1.00 KDM4C (0.47) KDM4CKDM4APHF8KDM2ALTA4H
SCHEMBL13684744 1.00 KDM4C (0.47) KDM4CKDM4APHF8KDM2ALTA4H
SCHEMBL15197954 0.98 LTA4H (0.45) KDM4CKDM4APHF8KDM2ALTA4H
SCHEMBL11117049 0.90 CA1 (0.44) KDM4CKDM4APHF8KDM2ALTA4H
SCHEMBL26202270 0.88 KDM4C (0.44) KDM4CKDM4APHF8KDM2ALTA4H
SCHEMBL9973392 0.87 CES2 (0.48) LTA4HLMNACES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240025863-A1 SOS1 PROTEIN DEGRADERS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND THEIR THERAPEUTIC APPLICATIONS BIOTHERYX, INC. 2024-01-25 US disclosed
US-20230321251-A1 LIPOSOME FORMULATION CONTAINING ANTIBACTERIAL AGENT OSAKA UNIVERSITY (JP) 2023-10-12 US disclosed
US-20230227826-A1 UNA OLIGOMERS FOR THE TREATMENT OF POLYGLUTAMINE DISEASES ARCTURUS THERAPEUTICS, INC. 2023-07-20 US disclosed
US-20230158159-A1 CHIMERIC DEGRADERS OF CYCLIN-DEPENDENT KINASE 9 AND USES THEREOF MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2023-05-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230321251-A1 LIPOSOME FORMULATION CONTAINING ANTIBACTERIAL AGENT LIPA, LIPG, LIPC KDM4C 3707/4885KDM4A 3081/4885PHF8 3678/4885
US-20230227826-A1 UNA OLIGOMERS FOR THE TREATMENT OF POLYGLUTAMINE DISEASES HNRNPR, HNRNPK, ATXN2 KDM4C 4179/4885KDM4A 4386/4885PHF8 2712/4885
US-20230158159-A1 CHIMERIC DEGRADERS OF CYCLIN-DEPENDENT KINASE 9 AND USES THEREOF CDK9, CDK19, CRBN KDM4C 507/4885KDM4A 388/4885PHF8 1832/4885
US-20240025863-A1 SOS1 PROTEIN DEGRADERS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND THEIR THERAPEUTIC APPLICATIONS SOS1, SOS2, SOST KDM4C 4432/4885KDM4A 3478/4885PHF8 3065/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.