Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.82 |
| ▸ | USP2 | O75604 | 2/20 | 0.82 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.82 |
| ▸ | NPC1 | O15118 | 1/20 | 0.82 |
| ▸ | MAPT | P10636 | 1/20 | 0.82 |
| ▸ | RAB9A | P51151 | 1/20 | 0.82 |
| ▸ | GUSB | P08236 | 1/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.76 |
| ▸ | GAA | P10253 | 1/20 | 0.76 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.76 |
| ▸ | MEN1 | O00255 | 3/20 | 0.73 |
| ▸ | LMNA | P02545 | 2/20 | 0.72 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.71 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.71 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.71 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.71 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.71 |
| ▸ | TSHR | P16473 | 1/20 | 0.71 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.71 |
| ▸ | CA2 | P00918 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25481989 | 0.92 | ALDH1A1 (0.78) | ALDH1A1USP2NPSR1NPC1MAPT | |
| SCHEMBL25482008 | 0.92 | L3MBTL1 (0.78) | ALDH1A1USP2NPSR1NPC1MAPT | |
| SCHEMBL25482037 | 0.86 | ALDH1A1 (0.74) | ALDH1A1USP2NPSR1NPC1MAPT | |
| SCHEMBL25482090 | 0.86 | ALDH1A1 (0.74) | ALDH1A1USP2NPSR1NPC1MAPT | |
| SCHEMBL16844168 | 0.79 | KMT2A (0.73) | ALDH1A1USP2NPSR1NPC1MAPT | |
| SCHEMBL2723919 | 0.78 | TP53 (0.73) | ALDH1A1USP2NPSR1NPC1MAPT | |
| SCHEMBL25482072 | 0.76 | KMT2A (0.78) | ALDH1A1NPSR1MAPTKMT2AMAPK1 | |
| SCHEMBL2722509 | 0.76 | KMT2A (0.84) | ALDH1A1NPSR1MAPTGUSBKMT2A | |
| SCHEMBL25482005 | 0.75 | TDP1 (0.70) | ALDH1A1USP2NPSR1MAPTKMT2A | |
| SCHEMBL25482016 | 0.74 | LMNA (0.82) | ALDH1A1NPSR1NPC1GUSBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230158028-A1 | COMPOUNDS AND METHODS FOR INDUCING UCP1 EXPRESSION | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2023-05-25 | — | — | US | disclosed |
| US-20230158028-A1 | COMPOUNDS AND METHODS FOR INDUCING UCP1 EXPRESSION | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2023-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230158028-A1 | COMPOUNDS AND METHODS FOR INDUCING UCP1 EXPRESSION | TFAM, FABP4, CPT2 | ALDH1A1 1604/4885USP2 2293/4885NPSR1 3572/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.