Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | DGKA | P23743 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11288016 | 0.83 | NOTUM (0.50) | ALOX12TBXAS1BRD4RAB9ACYP4F2 | |
| SCHEMBL17256327 | 0.83 | CYP1A2 (0.44) | CYP1A2BRD4DGKAL3MBTL1RAB9A | |
| SCHEMBL22193741 | 0.82 | ALOX12 (0.49) | ALOX12LMNAKMT2ASMN1; SMN2TDP1 | |
| SCHEMBL6358200 | 0.81 | CYP1A2 (0.46) | CYP1A2BRD4LMNAL3MBTL1RAB9A | |
| SCHEMBL8744647 | 0.80 | ALOX12 (0.46) | ALOX12BRD4LMNADGKAL3MBTL1 | |
| SCHEMBL14866439 | 0.79 | ALOX12 (0.46) | ALOX12BRD4LMNADGKAKMT2A | |
| SCHEMBL4700272 | 0.79 | BRD4 (0.42) | CYP1A2BRD4LMNADGKAL3MBTL1 | |
| SCHEMBL8652116 | 0.78 | ALOX12 (0.56) | ALOX12TBXAS1LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL21352287 | 0.78 | DGKA (0.42) | ALOX12LMNADGKAKMT2ASMN1; SMN2 | |
| SCHEMBL7466378 | 0.78 | SMN1; SMN2 (0.50) | CYP1A2L3MBTL1RAB9ASMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230151411-A1 | SELECTIVELY CONTROLLABLE CLEAVABLE LINKERS | MICROSOFT TECHNOLOGY LICENSING, LLC | 2023-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230151411-A1 | SELECTIVELY CONTROLLABLE CLEAVABLE LINKERS | DNPEP, ADAM8, ADAM10 | ALOX12 2824/4885CYP1A2 1921/4885TBXAS1 3767/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.