Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP1 | P53582 | 14/20 | 0.97 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | NCF1 | P14598 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31310819 | 1.00 | METAP1 (0.97) | METAP1L3MBTL1KDM4EKMT2AMEN1 | |
| SCHEMBL2547815 | 0.99 | METAP1 (1.00) | METAP1L3MBTL1KDM4EKMT2AMEN1 | |
| SCHEMBL31310818 | 0.99 | METAP1 (1.00) | METAP1L3MBTL1KDM4EKMT2AMEN1 | |
| SCHEMBL2545683 | 0.88 | METAP1 (1.00) | METAP1MAPK1NCF1 | |
| SCHEMBL9437189 | 0.81 | L3MBTL1 (1.00) | METAP1L3MBTL1KDM4EKMT2AMEN1 | |
| SCHEMBL10760751 | 0.78 | METAP1 (0.62) | METAP1L3MBTL1KDM4ECYP2C9 | |
| SCHEMBL2536200 | 0.75 | METAP1 (0.58) | METAP1L3MBTL1KDM4EKMT2ACYP2C9 | |
| SCHEMBL30511704 | 0.74 | NCF1 (0.97) | METAP1L3MBTL1KDM4EKMT2AMEN1 | |
| SCHEMBL2535257 | 0.74 | METAP1 (0.61) | METAP1L3MBTL1KDM4EKMT2ACYP2C9 | |
| SCHEMBL2534187 | 0.74 | METAP1 (0.61) | METAP1L3MBTL1KDM4EKMT2ACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8993470-B2 | Catalysts for the alkyne metathesis | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2015-03-31 | — | — | US | claimed |
| EP-2556078-B1 | CATALYSTS FOR ALKYNE METATHESIS | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2014-09-24 | — | — | EP | claimed |
| US-20130144102-A1 | CATALYSTS FOR THE ALKYNE METATHESIS | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2013-06-06 | — | — | US | claimed |
| EP-2556078-A1 | CATALYSTS FOR ALKYNE METATHESIS | Studiengesellschaft Kohle MbH (DE) | 2013-02-13 | — | — | EP | claimed |
| WO-2011120508-A1 | CATALYSTS FOR ALKYNE METATHESIS | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2011-10-06 | — | — | WO | claimed |
| EP-4484463-A1 | POLYMERIZABLE COMPOSITION OF CYCLIC OLEFINIC MONOMERS AND ASSOCIATED RING-OPENING METATHESIS POLYMERIZATION PROCESS | Telene SAS (FR) | 2025-01-01 | — | — | EP | disclosed |
| US-9233362-B2 | Molybdenum and tungsten metal complexes and use thereof as precatalysts for olefin metathesis | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2016-01-12 | — | — | US | disclosed |
| EP-2680967-B1 | MOLYBDENUM AND TUNGSTEN METAL COMPLEXES AND USE THEREOF AS PRECATALYSTS FOR OLEFIN METATHESIS | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2015-05-13 | — | — | EP | disclosed |
| US-8993470-B2 | Catalysts for the alkyne metathesis | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2015-03-31 | — | — | US | disclosed |
| US-20140296516-A1 | MOLYBDENUM AND TUNGSTEN METAL COMPLEXES AND USE THEREOF AS PRECATALYSTS FOR OLEFIN METATHESIS | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2014-10-02 | — | — | US | disclosed |
| EP-2556078-B1 | CATALYSTS FOR ALKYNE METATHESIS | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2014-09-24 | — | — | EP | disclosed |
| EP-2680967-A1 | MOLYBDENUM AND TUNGSTEN METAL COMPLEXES AND USE THEREOF AS PRECATALYSTS FOR OLEFIN METATHESIS | Studiengesellschaft Kohle MbH (DE) | 2014-01-08 | — | — | EP | disclosed |
| US-20130144102-A1 | CATALYSTS FOR THE ALKYNE METATHESIS | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2013-06-06 | — | — | US | disclosed |
| EP-2556078-A1 | CATALYSTS FOR ALKYNE METATHESIS | Studiengesellschaft Kohle MbH (DE) | 2013-02-13 | — | — | EP | disclosed |
| WO-2012116695-A1 | MOLYBDENUM AND TUNGSTEN METAL COMPLEXES AND USE THEREOF AS PRECATALYSTS FOR OLEFIN METATHESIS | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2012-09-07 | — | — | WO | disclosed |
| WO-2011120508-A1 | CATALYSTS FOR ALKYNE METATHESIS | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2011-10-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140296516-A1 | MOLYBDENUM AND TUNGSTEN METAL COMPLEXES AND USE THEREOF AS PRECATALYSTS FOR OLEFIN METATHESIS | MSRB3, RO60, RTF1 | METAP1 2284/4885L3MBTL1 1876/4885KDM4E 4285/4885 |
| US-20130144102-A1 | CATALYSTS FOR THE ALKYNE METATHESIS | MSH6, AP3M1, PMS2 | METAP1 259/4885L3MBTL1 852/4885KDM4E 4138/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.