Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 1/20 | 0.40 |
| ▸ | ACACA | Q13085 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | BCR | P11274 | 1/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25529789 | 0.92 | MAPT (0.37) | PIN1ACACAHPGDKDM4ESMN1; SMN2 | |
| SCHEMBL26861790 | 0.75 | NPC1 (0.48) | ACACAHPGDKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL7534594 | 0.75 | GPR84 (0.42) | PIN1ACACAHPGDKDM4ESMN1; SMN2 | |
| SCHEMBL5107921 | 0.75 | L3MBTL1 (0.40) | HPGDKDM4ESMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL5178952 | 0.73 | MEN1 (0.36) | PIN1HPGDKDM4EALDH1A1KMT2A | |
| SCHEMBL19891942 | 0.73 | ALDH1A1 (0.34) | PIN1ACACAHPGDKDM4ESMN1; SMN2 | |
| SCHEMBL7213739 | 0.73 | MAPT (0.46) | HPGDKDM4ESMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL7263818 | 0.73 | ACACA (0.38) | PIN1ACACAHPGDKDM4EALDH1A1 | |
| SCHEMBL25607194 | 0.73 | KDM4E (0.33) | PIN1ACACAHPGDKDM4EALDH1A1 | |
| SCHEMBL25607147 | 0.72 | KDM4E (0.34) | PIN1HPGDKDM4ESMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159818-A1 | PHOTOCHROMIC COMPOSITIONS | NANO AND ADVANCED MATERIALS INSTITUTE LIMITED (HK) | 2023-05-25 | — | — | US | disclosed |