Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 8/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.50 |
| ▸ | COPS5 | Q92905 | 6/20 | 0.49 |
| ▸ | PSMD14 | O00487 | 6/20 | 0.49 |
| ▸ | STAMBP | O95630 | 6/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL617662 | 0.82 | HTT (0.46) | NAMPTMAPK1 | |
| SCHEMBL253124 | 0.78 | STAMBP (0.44) | NAMPTMAPK1COPS5PSMD14STAMBP | |
| SCHEMBL252709 | 0.76 | STAMBP (0.55) | NAMPTMAPK1COPS5PSMD14STAMBP | |
| SCHEMBL253871 | 0.73 | HPGDS (0.60) | NAMPTCOPS5PSMD14STAMBP | |
| SCHEMBL619249 | 0.73 | HTT (0.48) | — | |
| SCHEMBL250787 | 0.72 | HTT (0.47) | MAPK1 | |
| SCHEMBL252287 | 0.71 | STAMBP (0.51) | NAMPTCOPS5PSMD14STAMBP | |
| SCHEMBL619626 | 0.71 | MAPK1 (0.45) | MAPK1 | |
| SCHEMBL253706 | 0.71 | MLYCD (0.58) | NAMPTCOPS5PSMD14STAMBP | |
| SCHEMBL255347 | 0.71 | SYK (0.38) | MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2401275-A1 | NOVEL BRONCHODILATING DIAZAHETEROARYLS | Respiratorius AB (SE) | 2012-01-04 | — | — | EP | claimed |